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![14-3-3 Recombinant Rabbit Monoclonal Antibody [JJ083-6] — image 1 of 2](https://cdn.genprice.uk/products/992/68dd1c8a061270361ea80e84/imageurl/et1701-2.webp)
Product details
Catalog number ET1701-2
Price for ET1701-2
Size / count 100 µL
14-3-3 proteins are a family of conserved regulatory molecules that are expressed in all eukaryotic cells. 14-3-3 proteins have the ability to bind a multitude of functionally diverse signaling proteins, including kinases, phosphatases, and transmembrane receptors. More than 200 signaling proteins have been reported as 14-3-3 ligands. 14-3-3 proteins play an isoform-specific role in class switch recombination. They are believed to interact with the protein Activation-Induced (Cytidine) Deaminase in mediating class switch recombination. Phosphorylation of Cdc25C by CDS1 and CHEK1 creates a binding site for the 14-3-3 family of phosphoserine binding proteins. Binding of 14-3-3 has little effect on Cdc25C activity, and it is believed that 14-3-3 regulates Cdc25C by sequestering it to the cytoplasm, thereby preventing the interactions with CycB-Cdk1 that are localized to the nucleus at the G2/M transition.
The catalog number for 14-3-3 Recombinant Rabbit Monoclonal Antibody [JJ083-6] is ET1701-2.
14-3-3 Recombinant Rabbit Monoclonal Antibody [JJ083-6] is available in the following size(s): 100 µL.
14-3-3 Recombinant Rabbit Monoclonal Antibody [JJ083-6] is currently made to order / not held in immediate stock. Contact us for lead time.
14-3-3 proteins are a family of conserved regulatory molecules that are expressed in all eukaryotic cells. 14-3-3 proteins have the ability to bind a multitude of functionally diverse signaling proteins, including kinases, phosphatases, and transmembrane receptors. More than 200 signaling proteins h
The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.
A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.
Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.
