Phospho-B Raf (T401) Recombinant Rabbit Monoclonal Antibody [JJ08-72] — image 1 of 3

Product details

Phospho-B Raf (T401) Recombinant Rabbit Monoclonal Antibody [JJ08-72]

Catalog number ET1701-20

Price for ET1701-20

Size / count 100 µL

About this product

BRAF is a human gene that encodes a protein called B-Raf. The gene is also referred to as proto-oncogene B-Raf and v-Raf murine sarcoma viral oncogene homolog B, while the protein is more formally known as serine/threonine-protein kinase B-Raf. B-Raf is a member of the Raf kinase family of growth signal transduction protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. The B-Raf protein is involved in sending signals inside cells which are involved in directing cell growth. Certain other inherited BRAF mutations cause birth defects. Drugs that treat cancers driven by BRAF mutations have been developed. Two of these drugs, vemurafenib and dabrafenib are approved by FDA for treatment of late-stage melanoma.

Specifications

Catalog number: ET1701-20
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: FLJ95109 antibody 94 kDa B raf protein antibody B raf 1 antibody B Raf proto oncogene serine threonine protein kinase antibody B Raf proto oncogene, serine/threonine kinase antibody B RAF1 antibody B-Raf proto-oncogene serine/threonine-protein kinase (p94) antibody BRAF 1 antibody BRAF antibody BRAF_HUMAN antibody BRAF1 antibody cRmil antibody MGC126806 antibody MGC138284 antibody Murine sarcoma viral (v-raf) oncogene homolog B1 antibody Murine sarcoma viral v raf oncogene homolog B1 antibody NS7 antibody Oncogen BRAF antibody oncogene BRAF1 antibody p94 antibody Proto-oncogene B-Raf antibody Proto-oncogene c-Rmil antibody RAFB 1 antibody RAFB1 antibody RMIL antibody Serine/threonine-protein kinase B-raf antibody v raf murine sarcoma viral oncogene homolog B antibody v raf murine sarcoma viral oncogene homolog B1 antibody v-Raf murine sarcoma viral oncogene homolog B1 antibody
Abbreviation: BRAF
Swiss Prot: P15056 Human, P28028 Mouse,
Cellular Locus: Nucleus, Cytoplasm, Cell membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Thr401 of Human B Raf aa 371-420 / 766.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IP
Positive Control: Mouse testis tissue lysates, PC-12 cell lysates, PC-3M, MCF-7, PC-12.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IF-Cell: 1:100-1:500 ;IP: Use at an assay dependent concentration.
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 84 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Phospho-B Raf (T401) Recombinant Rabbit Monoclonal Antibody [JJ08-72]?

The catalog number for Phospho-B Raf (T401) Recombinant Rabbit Monoclonal Antibody [JJ08-72] is ET1701-20.

What sizes are available for Phospho-B Raf (T401) Recombinant Rabbit Monoclonal Antibody [JJ08-72]?

Phospho-B Raf (T401) Recombinant Rabbit Monoclonal Antibody [JJ08-72] is available in the following size(s): 100 µL.

Is Phospho-B Raf (T401) Recombinant Rabbit Monoclonal Antibody [JJ08-72] in stock?

Phospho-B Raf (T401) Recombinant Rabbit Monoclonal Antibody [JJ08-72] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Phospho-B Raf (T401) Recombinant Rabbit Monoclonal Antibody [JJ08-72] used for?

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.