CD36 Recombinant Rabbit Monoclonal Antibody [JJ2005]

About this product

CD36 (cluster of differentiation 36), also known as platelet glycoprotein 4, fatty acid translocase (FAT), scavenger receptor class B member 3 (SCARB3), and glycoproteins 88 (GP88), IIIb (GPIIIB), or IV (GPIV) is a protein that in humans is encoded by the CD36 gene. The CD36 antigen is an integral membrane protein found on the surface of many cell types in vertebrate animals. It imports fatty acids inside cells and is a member of the class B scavenger receptor family of cell surface proteins. CD36 binds many ligands including collagen, thrombospondin, erythrocytes parasitized with Plasmodium falciparum, oxidized low density lipoprotein, native lipoproteins, oxidized phospholipids, and long-chain fatty acids. Work in genetically modified rodents suggest a role for CD36 in fatty acid metabolism, heart disease, taste, and dietary fat processing in the intestine. It may be involved in glucose intolerance, atherosclerosis, arterial hypertension, diabetes, cardiomyopathy, Alzheimer's disease and various cancers, mostly of epithelial origin (breast, prostate, ovary, and colon) and also for hepatic carcinoma and gliomas.

Specifications

Catalog number

ET1701-24

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

CAS Number

9000-83-3

Product Name Alternative

Adipocyte membrane protein antibody BDPLT10 antibody CD36 antibody CD36 antigen (collagen type I receptor, thrombospondin receptor) antibody CD36 antigen antibody CD36 molecule (thrombospondin receptor) antibody CD36 molecule antibody CD36_HUMAN antibody CHDS7 antibody Cluster determinant 36 antibody Collagen receptor, platelet antibody FAT antibody Fatty acid translocase antibody Fatty acid transport protein antibody Glycoprotein IIIb antibody GP IIIb antibody GP3B antibody GP4 antibody GPIIIB antibody GPIV antibody Leukocyte differentiation antigen CD36 antibody MGC108510 antibody MGC91634 antibody PAS 4 protein antibody PAS IV antibody PAS-4 antibody PASIV antibody Platelet collagen receptor antibody Platelet glycoprotein 4 antibody Platelet glycoprotein IV antibody scarb3 antibody Scavenger receptor class B member 3 antibody Thrombospondin receptor antibody

Abbreviation

FAT, GPIIIB, GPIV, CD36

Swiss Prot

P16671 Human, Q08857 Mouse, Q07969 Rat

Cellular Locus

Cell membrane, Membrane raft, Golgi apparatus, Apical cell membrane.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human CD36 aa 360-373 / 472.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, FC, IP

Positive Control

Human heart tissue lysate, Mouse heart tissue lysate, THP-1, THP-1 cells treated with 100ng/mL PMA for 72 hours, human spleen tissue, mouse spleen tissue, mouse heart tissue, mouse lung tissue, mouse stomach tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:1,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100 ;IP: Use at an assay dependent concentration.

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 53 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes