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![ATF7 Recombinant Rabbit Monoclonal Antibody [JJ2-072] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8c061270361ea81cd3/imageurl/et1701-31.webp)
Product details
Catalog number ET1701-31
Price for ET1701-31
Size / count 100 µL
Stress-responsive chromatin regulator that plays a role in various biological processes including innate immunological memory, adipocyte differentiation or telomerase regulation. In absence of stress, contributes to the formation of heterochromatin and heterochromatin-like structure by recruiting histone H3K9 tri- and di-methyltransferases thus silencing the transcription of target genes such as STAT1 in adipocytes, or genes involved in innate immunity in macrophages and adipocytes (By similarity). Stress induces ATF7 phosphorylation that disrupts interactions with histone methyltransferase and enhances the association with coactivators containing histone acetyltransferase and/or histone demethylase, leading to disruption of the heterochromatin-like structure and subsequently transcriptional activation (By similarity). In response to TNF-alpha, which is induced by various stresses, phosphorylated ATF7 and telomerase are released from telomeres leading to telomere shortening. Plays also a role in maintaining epithelial regenerative capacity and protecting against cell death during intestinal epithelial damage and repair (By similarity).
The catalog number for ATF7 Recombinant Rabbit Monoclonal Antibody [JJ2-072] is ET1701-31.
ATF7 Recombinant Rabbit Monoclonal Antibody [JJ2-072] is available in the following size(s): 100 µL.
ATF7 Recombinant Rabbit Monoclonal Antibody [JJ2-072] is currently made to order / not held in immediate stock. Contact us for lead time.
Stress-responsive chromatin regulator that plays a role in various biological processes including innate immunological memory, adipocyte differentiation or telomerase regulation. In absence of stress, contributes to the formation of heterochromatin and heterochromatin-like structure by recruiting hi
A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.
Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.
Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.
