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Product details

GLUT2 Recombinant Rabbit Monoclonal Antibody [JJ20-21]

Catalog number ET1701-34

Price for ET1701-34

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Size / count 100 µL

About this product

Glucose transporter 2 (GLUT2) also known as solute carrier family 2 (facilitated glucose transporter), member 2 (SLC2A2) is a transmembrane carrier protein that enables protein facilitated glucose movement across cell membranes. It is the principal transporter for transfer of glucose between liver and blood. Unlike GLUT4, it does not rely on insulin for facilitated diffusion. GLUT2 has high capacity for glucose but low affinity (high KM, ca. 15–20 mM) and thus functions as part of the "glucose sensor" in the pancreatic β-cells of rodents, though in human β-cells the role of GLUT2 seems to be a minor one. It is a very efficient carrier for glucose. GLUT2 also carries glucosamine. When the glucose concentration in the lumen of the small intestine goes above 30 mM, such as occurs in the fed-state, GLUT2 is up-regulated at the brush border membrane, enhancing the capacity of glucose transport. Basolateral GLUT2 in enterocytes also aids in the transport of fructose into the bloodstream through glucose-dependent cotransport.

Specifications

Catalog number
ET1701-34
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
liver antibody Glucose Transporter 2 antibody Glucose Transporter GLUT2 antibody Glucose transporter type 2 antibody Glucose transporter type 2 liver antibody Glucose transporter, liver/islet antibody GLUT-2 antibody GLUT2 antibody GTR2_HUMAN antibody GTT2 antibody SLC2A2 antibody Solute carrier family 2 (facilitated glucose transporter) member 2 antibody Solute carrier family 2 facilitated glucose transporter member 2 antibody Solute carrier family 2, facilitated glucose transporter member 2 antibody
Abbreviation
GLUT-2, SLC2A2
Swiss Prot
P11168 Human
Cellular Locus
Membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human Glucose Transporter GLUT2 aa 35-84 / 524.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
A549 cell lysates, human liver tissue, human kidney tissue, human pancreas tissue, HepG2.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 57 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for GLUT2 Recombinant Rabbit Monoclonal Antibody [JJ20-21]?

The catalog number for GLUT2 Recombinant Rabbit Monoclonal Antibody [JJ20-21] is ET1701-34.

What sizes are available for GLUT2 Recombinant Rabbit Monoclonal Antibody [JJ20-21]?

GLUT2 Recombinant Rabbit Monoclonal Antibody [JJ20-21] is available in the following size(s): 100 µL.

Is GLUT2 Recombinant Rabbit Monoclonal Antibody [JJ20-21] in stock?

GLUT2 Recombinant Rabbit Monoclonal Antibody [JJ20-21] is currently made to order / not held in immediate stock. Contact us for lead time.

What is GLUT2 Recombinant Rabbit Monoclonal Antibody [JJ20-21] used for?

Glucose transporter 2 (GLUT2) also known as solute carrier family 2 (facilitated glucose transporter), member 2 (SLC2A2) is a transmembrane carrier protein that enables protein facilitated glucose movement across cell membranes. It is the principal transporter for transfer of glucose between liver a

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

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