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![Phospho-JunD (S255) Recombinant Rabbit Monoclonal Antibody [JJ08-21] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c90061270361ea828ae/imageurl/et1701-35.webp)
Product details
Catalog number ET1701-35
Price for ET1701-35
Size / count 100 µL
Transcription factor JunD is a protein that in humans is encoded by the JUND gene. The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternate translation initiation site usage results in the production of different isoforms. The dominant negative mutant variant of JunD, known as ΔJunD or Delta JunD, is a potent antagonist of the ΔFosB transcript, as well as other forms of AP-1-mediated transcriptional activity. In the nucleus accumbens, ΔJunD directly opposes many of the neurological changes that occur in addiction (i.e., those induced by ΔFosB). ΔFosB inhibitors (drugs that oppose its action) may be an effective treatment for addiction and addictive disorders. Being an unnatural genetic variant, deltaJunD has not been observed in humans. JunD has been shown to interact with ATF3, MEN1, DNA damage-inducible transcript 3 and BRCA1.
The catalog number for Phospho-JunD (S255) Recombinant Rabbit Monoclonal Antibody [JJ08-21] is ET1701-35.
Phospho-JunD (S255) Recombinant Rabbit Monoclonal Antibody [JJ08-21] is available in the following size(s): 100 µL.
Phospho-JunD (S255) Recombinant Rabbit Monoclonal Antibody [JJ08-21] is currently made to order / not held in immediate stock. Contact us for lead time.
Transcription factor JunD is a protein that in humans is encoded by the JUND gene. The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence and ap
Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.
Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.
Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.
