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Product details

IL-1 beta Recombinant Rabbit Monoclonal Antibody [JJ087-3]

Catalog number ET1701-39

Price for ET1701-39

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Size / count 100 µL

About this product

Two forms of interleukin-1, designated IL-1α and IL-1β, have been described. Although encoded by distinct genes and exhibiting roughly only 25% sequence identity, IL-1α and IL-1β bind to the same receptor and seem to elicit similar biological responses. IL-1 production is generally thought to be associated with inflammation, but it has also been shown to be expressed during kidney development, thymocyte differentiation and cartilage degradation. IL-1 plays a critical role in the regulation of immune response and inflammation, acting as an activator of T and B lymphocytes and natural killer (NK) cells. In T cells, IL-1 stimulates the production of IL-2 and selectively inhibits IL-4 expression. IL-1 induces B cell proliferation and maturation, and immunoglobulin synthesis. NK cells require IL-1β for production of the anti- pathogen IFN-γ. IL-1 has also been implicated in several pathological conditions including rheumatoid arthritis, inflammatory bowel disease and atherosclerosis.

Specifications

Catalog number
ET1701-39
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Catabolin antibody H1 antibody IL 1 antibody IL 1 beta antibody IL-1 beta antibody IL1 BETA antibody IL1B antibody IL1B_HUMAN antibody IL1F2 antibody Interleukin 1 beta antibody Interleukin-1 beta antibody OAF antibody OTTHUMP00000162031 antibody Preinterleukin 1 beta antibody Pro interleukin 1 beta antibody
Abbreviation
IL-1 beta, IL1B
Swiss Prot
P01584 Human
Cellular Locus
Cytoplasm, Lysosome, extracellular exosome, Secreted.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within C-terminal human IL1 beta.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P, FC
Positive Control
THP-1 treated with 80nM TPA overnight then treated with 100ng/mL LPS for 6 hours and 300ng/mL BFA for 3 hours whole cell lysate, A431, Hela, human kidney tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 31 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for IL-1 beta Recombinant Rabbit Monoclonal Antibody [JJ087-3]?

The catalog number for IL-1 beta Recombinant Rabbit Monoclonal Antibody [JJ087-3] is ET1701-39.

What sizes are available for IL-1 beta Recombinant Rabbit Monoclonal Antibody [JJ087-3]?

IL-1 beta Recombinant Rabbit Monoclonal Antibody [JJ087-3] is available in the following size(s): 100 µL.

Is IL-1 beta Recombinant Rabbit Monoclonal Antibody [JJ087-3] in stock?

IL-1 beta Recombinant Rabbit Monoclonal Antibody [JJ087-3] is currently made to order / not held in immediate stock. Contact us for lead time.

What is IL-1 beta Recombinant Rabbit Monoclonal Antibody [JJ087-3] used for?

Two forms of interleukin-1, designated IL-1α and IL-1β, have been described. Although encoded by distinct genes and exhibiting roughly only 25% sequence identity, IL-1α and IL-1β bind to the same receptor and seem to elicit similar biological responses. IL-1 production is generally thought to be ass

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

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