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Product details

STAT4 Recombinant Rabbit Monoclonal Antibody [JJ08-85]

Catalog number ET1701-42

Price for ET1701-42

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Size / count 100 µL

About this product

Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-a and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3β appears to be activated by both while Stat3α is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.

Specifications

Catalog number
ET1701-42
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Signal transducer and activator of transcription 4 antibody SLEB11 antibody STAT4 antibody STAT4_HUMAN antibody
Abbreviation
STAT4
Swiss Prot
Q14765 Human, P42228 Mouse,
Cellular Locus
Cytoplasm, Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human STAT4 aa 700-748.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P, FC, IP
Positive Control
SiHa cell lysate, A549 cell lysate, HeLa cell lysate, MCF7 cell lysate, SW480 cell lysate, HeLa, human colon carcinoma tissue, human tonsils tissue, mouse testis tissue, rat testis tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IF-Cell: 1:100-1:500 ;IF-Tissue: 1:100-1:500 ;IHC-P: 1:50-1:1,000 ;FC: 1:1,000 ;IP: Use at an assay dependent concentration.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 86 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for STAT4 Recombinant Rabbit Monoclonal Antibody [JJ08-85]?

The catalog number for STAT4 Recombinant Rabbit Monoclonal Antibody [JJ08-85] is ET1701-42.

What sizes are available for STAT4 Recombinant Rabbit Monoclonal Antibody [JJ08-85]?

STAT4 Recombinant Rabbit Monoclonal Antibody [JJ08-85] is available in the following size(s): 100 µL.

Is STAT4 Recombinant Rabbit Monoclonal Antibody [JJ08-85] in stock?

STAT4 Recombinant Rabbit Monoclonal Antibody [JJ08-85] is currently made to order / not held in immediate stock. Contact us for lead time.

What is STAT4 Recombinant Rabbit Monoclonal Antibody [JJ08-85] used for?

Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-a and form a heterodimer which is part o

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

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