Product details
Catalog number ET1701-42
Price for ET1701-42
Size / count 100 µL
Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-a and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3β appears to be activated by both while Stat3α is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.
The catalog number for STAT4 Recombinant Rabbit Monoclonal Antibody [JJ08-85] is ET1701-42.
STAT4 Recombinant Rabbit Monoclonal Antibody [JJ08-85] is available in the following size(s): 100 µL.
STAT4 Recombinant Rabbit Monoclonal Antibody [JJ08-85] is currently made to order / not held in immediate stock. Contact us for lead time.
Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-a and form a heterodimer which is part o
A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.
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