MEK3+MEK6 Recombinant Rabbit Monoclonal Antibody [JJ087-09]

About this product

A family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.

Specifications

Catalog number

ET1701-48

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Dual specificity mitogen activated protein kinase kinase 6 antibody Dual specificity mitogen-activated protein kinase kinase 3 antibody MAP kinase kinase 3 antibody MAP kinase kinase 6 antibody map2k3 antibody MAP2K6 antibody MAPK/ERK kinase 3 antibody MAPK/ERK kinase 6 antibody MAPKK 3 antibody MAPKK 6 antibody MAPKK3 antibody MAPKK6 antibody MEK 3 antibody MEK 6 antibody Mitogen activated protein kinase kinase 3 antibody Mitogen activated protein kinase kinase 6 antibody MKK3 antibody MKK6 antibody MP2K3_HUMAN antibody PRKMK3 antibody PRKMK6 antibody Protein kinase, mitogen activated, kinase 6 (MAP kinase kinase 6) antibody SAPK kinase 2 antibody SAPKK 3 antibody SAPKK-2 antibody SAPKK2 antibody SAPKK3 antibody Stress activated protein kinase kinase 3 antibody Stress-activated protein kinase kinase 2 antibody

Abbreviation

MAP kinase kinase 3, MAPKK 3, MEK 3, SAPK kinase 2, SAPKK-2, SAPKK2, MAP2K3, MAP kinase kinase 6, MAPKK 6, MEK 6, SAPK kinase 3, SAPKK-3, SAPKK3, MAP2K6

Swiss Prot

P46734 Human, P52564 Human, O09110 Mouse, P70236 Mouse,

Cellular Locus

Cytoplasm, Cytoskeleton, Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human MEK3+MEK6 aa 298-347 / 347.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, FC, IP

Positive Control

Hela cell lysate, Jurkat cell lysate, Hela, HepG2, NIH/3T3, human colon tissue, mouse colon tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:2,000;IF-Cell: 1:50-1:200;IF-Tissue: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100;IP: Use at an assay dependent concentration.

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 39/37 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes