PAX5 Recombinant Rabbit Monoclonal Antibody [JJ08-87]

About this product

Paired box protein Pax-5 is a protein that in humans is encoded by the PAX5 gene. The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding domain, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.

Specifications

Catalog number

ET1701-49

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

B cell lineage specific activator antibody B cell lineage specific activator protein antibody B cell specific activator protein antibody B cell specific transcription factor antibody B-cell-specific transcription factor antibody BSAP antibody EBB-1 antibody KLP antibody Paired box 5 antibody Paired box gene 5 (B cell lineage specific activator protein) antibody Paired box gene 5 (B cell lineage specific activator) antibody Paired box gene 5 antibody Paired box homeotic gene 5 antibody Paired box protein Pax 5 antibody Paired box protein Pax-5 antibody Paired domain gene 5 antibody PAX 5 antibody PAX5 antibody PAX5_HUMAN antibody Transcription factor PAX 5 antibody

Abbreviation

PAX5

Swiss Prot

Q02548 Human, Q02650 Mouse,

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within human PAX5 aa 240-280.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, FC

Positive Control

Daudi cell lysate, Raji cell lysate, A20 cell lysate, human lymph nodes tissue, human tonsil tissue, human spleen tissue, mouse spleen tissue, rat spleen tissue, human appendix tissue, human B cell lymphoma tissue, Raji.

Concentration

1 mg/mL

Dilution

WB: 1:5,000 ;IF-Cell: 1:500 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:1,000-1:2,000 ;FC: 1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 42 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes