Caspase-14 Recombinant Rabbit Monoclonal Antibody [JJ089-01] — image 1 of 3

Product details

Caspase-14 Recombinant Rabbit Monoclonal Antibody [JJ089-01]

Catalog number ET1701-52

Price for ET1701-52

Size / count 100 µL

About this product

A unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, Ced-3/caspase-1, is composed of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6 and caspase-7 (also designated Mch3, ICE-LAP3 or CMH-1), caspase-9, caspase-10, and caspase-14. Ced-3/caspase-1 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Caspase-3, caspase-7 and caspase-9, but not caspase-1, have been shown to cleave the nuclear protein PARP into an apoptotic fragment. Caspase-14, also designated MICE (for mini-ICE), is highly expressed in embryonic tissues but appears to be absent from adult tissues. Procaspase-14 can be processed in vitro by caspase-8 and caspase-10 but not by other caspases.

Specifications

Catalog number: ET1701-52
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Caspase14 Apoptosis related cysteine protease antibody CASP 14 antibody CASP-14 antibody CASP14 antibody Caspase 14 apoptosis related cysteine protease antibody Caspase 14 precursor antibody Caspase-14 subunit p10 antibody Caspase14 antibody CASPE_HUMAN antibody MGC119078 antibody MGC119079 antibody MICE antibody Mini ICE antibody
Abbreviation: CASP-14, CASP14
Swiss Prot: P31944 Human, O89094 Mouse
Cellular Locus: Cytoplasm, Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human Caspase-14 aa 80-220 / 242.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IHC-P, FC, IP
Positive Control: A431 cell lysates, MCF-7 cell lysates, HepG2, MCF-7, A431, human skin tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:200-1:1,000 ;IHC-P: 1:5,000 ;FC: 1:50-1:100 ;IP: Use at an assay dependent concentration.
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 28 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Caspase-14 Recombinant Rabbit Monoclonal Antibody [JJ089-01]?

The catalog number for Caspase-14 Recombinant Rabbit Monoclonal Antibody [JJ089-01] is ET1701-52.

What sizes are available for Caspase-14 Recombinant Rabbit Monoclonal Antibody [JJ089-01]?

Caspase-14 Recombinant Rabbit Monoclonal Antibody [JJ089-01] is available in the following size(s): 100 µL.

Is Caspase-14 Recombinant Rabbit Monoclonal Antibody [JJ089-01] in stock?

Caspase-14 Recombinant Rabbit Monoclonal Antibody [JJ089-01] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Caspase-14 Recombinant Rabbit Monoclonal Antibody [JJ089-01] used for?

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.