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![HDAC6 Recombinant Rabbit Monoclonal Antibody [JJ09-09] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8c061270361ea81b50/imageurl/et1701-66.webp)
Product details
Catalog number ET1701-66
Price for ET1701-66
Size / count 100 µL
In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBPassociated factor), p300/CBP, HAT1, and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated RPD3) and HDAC3-6, have been identified as histone deacetylases.
The catalog number for HDAC6 Recombinant Rabbit Monoclonal Antibody [JJ09-09] is ET1701-66.
HDAC6 Recombinant Rabbit Monoclonal Antibody [JJ09-09] is available in the following size(s): 100 µL.
HDAC6 Recombinant Rabbit Monoclonal Antibody [JJ09-09] is currently made to order / not held in immediate stock. Contact us for lead time.
In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. A
Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.
Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.
Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.
