- Home
- Shop
- New Categories
- New Blog
- Contact Us
- Cart
- Login
- Register
![Estrogen Receptor beta Recombinant Rabbit Monoclonal Antibody [JJ09-02] — image 1 of 1](https://cdn.genprice.uk/products/992/68dd1c8a061270361ea80ff5/imageurl/et1701-69.webp)
Select the image to view it full size.
Product details
Catalog number ET1701-69
Price for ET1701-69
Size / count 100 µL
Estrogen receptor beta (ERβ) also known as NR3A2 (nuclear receptor subfamily 3, group A, member 2) is one of two main types of estrogen receptor—a nuclear receptor which is activated by the sex hormone estrogen.[5] In humans ERβ is encoded by the ESR2 gene. ERβ is a member of the family of estrogen receptors and the superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17-β-estradiol, estriol or related ligands, the encoded protein forms homo-dimers or hetero-dimers with estrogen receptor α that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. ERβ may inhibit cell proliferation and opposes the actions of ERα in reproductive tissue. ERβ may also have an important role in adaptive function of the lung during pregnancy. ERβ is a potent tumor suppressor and plays a crucial role in many cancer types such as prostate cancer and ovarian cancer.
The catalog number for Estrogen Receptor beta Recombinant Rabbit Monoclonal Antibody [JJ09-02] is ET1701-69.
Estrogen Receptor beta Recombinant Rabbit Monoclonal Antibody [JJ09-02] is available in the following size(s): 100 µL.
Estrogen Receptor beta Recombinant Rabbit Monoclonal Antibody [JJ09-02] is currently made to order / not held in immediate stock. Contact us for lead time.
Estrogen receptor beta (ERβ) also known as NR3A2 (nuclear receptor subfamily 3, group A, member 2) is one of two main types of estrogen receptor—a nuclear receptor which is activated by the sex hormone estrogen.[5] In humans ERβ is encoded by the ESR2 gene. ERβ is a member of the family of estrogen
Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.
Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.
Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.
