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![Cystatin C Recombinant Rabbit Monoclonal Antibody [JJ09-16] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8a061270361ea80f46/imageurl/et1701-72.webp)
Product details
Catalog number ET1701-72
Price for ET1701-72
Size / count 100 µL
Cystatin C is a cysteine (thiol) protease inhibitor that belongs to the type II cystatin gene superfamily and is the most abundant extracellular inhibitor of cysteine proteases. Cystatin C is a constitutively secreted, amyloidogenic protein, which forms a two-fold symmetric dimer and modulates both cysteine protease activity and the expression of class II MHC molecules. Expression of cystatin C is an indicator of kidney function and glomerular filtration rate. Mutations in the cystatin C gene can lead to protein aggregates, which are implicated in hereditary amyloid angiopathy (HCCAA) and cerebral hemorrhage. Although both wild-type and mutant cystatin C are capable of forming concentration dependent inactive dimers, mutant cystatin C dimerizes at lower concentrations and is more susceptible to serine proteases, which may facilitate aggregation. In neuronal cells, oxidative stress stimulates expression of cystatin C, which may positively regulate apoptosis.
The catalog number for Cystatin C Recombinant Rabbit Monoclonal Antibody [JJ09-16] is ET1701-72.
Cystatin C Recombinant Rabbit Monoclonal Antibody [JJ09-16] is available in the following size(s): 100 µL.
Cystatin C Recombinant Rabbit Monoclonal Antibody [JJ09-16] is currently made to order / not held in immediate stock. Contact us for lead time.
Cystatin C is a cysteine (thiol) protease inhibitor that belongs to the type II cystatin gene superfamily and is the most abundant extracellular inhibitor of cysteine proteases. Cystatin C is a constitutively secreted, amyloidogenic protein, which forms a two-fold symmetric dimer and modulates both
A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.
Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.
Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.
