Occludin Recombinant Rabbit Monoclonal Antibody [JJ091-08]

Catalog number ET1701-76

Price for ET1701-76

Size / count 100 µL

About this product

Occludin is an integral membrane protein closely associated with the tight junctions of epithelial and endothelial cells. Occludin is a tetraspan integral membrane protein in epithelial and endothelial tight junction (TJ) structures that can contain two extracellular loops. The protein exists in a variety of phosphorylated forms. Phosphorylation is involved in regulating both the localization and the function of occludin. Expression of occludin is up-regulated by poly-unsaturated fatty acids, increasing transendothelial cell resistance and reducing cellular permeability to large molecules. The level of occludin varies greatly depending on tissue; in brain tissue, occludin is highly expressed at cell-cell contact sites. Non-neural tissues show lower expression and discontinuous distribution. Up-regulation of epithelial occludin may play a role in enhancing paracellular permeability and be related to the damage to the tight junction.

Specifications

Catalog number: ET1701-76
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: BLCPMG antibody FLJ08163 antibody FLJ18079 antibody FLJ77961 antibody FLJ94056 antibody MGC34277 antibody Occludin antibody Ocln antibody OCLN_HUMAN antibody Tight junction protein occludin antibody
Abbreviation: OCLN
Swiss Prot: Q16625 Human, Q61146 Mouse
Cellular Locus: Cell membrane, tight junction.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Synthetic peptide within N-terminal human Occludin.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IP, FC, IF-Cell
Positive Control: MCF-7 cell lysate, Mouse smooth muscle tissue lysate, Caco-2.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;FC: 1:1,000 ;IP: Use at an assay dependent concentration. ;IF-Cell: 1:500
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 59 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Occludin Recombinant Rabbit Monoclonal Antibody [JJ091-08]?

The catalog number for Occludin Recombinant Rabbit Monoclonal Antibody [JJ091-08] is ET1701-76.

What sizes are available for Occludin Recombinant Rabbit Monoclonal Antibody [JJ091-08]?

Occludin Recombinant Rabbit Monoclonal Antibody [JJ091-08] is available in the following size(s): 100 µL.

Is Occludin Recombinant Rabbit Monoclonal Antibody [JJ091-08] in stock?

Occludin Recombinant Rabbit Monoclonal Antibody [JJ091-08] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Occludin Recombinant Rabbit Monoclonal Antibody [JJ091-08] used for?

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.