DUSP1 Recombinant Rabbit Monoclonal Antibody [JJ0930] — image 1 of 3

Product details

DUSP1 Recombinant Rabbit Monoclonal Antibody [JJ0930]

Catalog number ET1701-82

Discontinued

Price for ET1701-82

Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation.

Specifications

Catalog number: ET1701-82
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
CAS Number: 9000-83-3
Product Name Alternative: CL 100 antibody CL100 antibody Dual Specificity Phosphatase 1 antibody Dual specificity protein phosphatase 1 antibody Dual specificity protein phosphatase hVH1 antibody DUS1_HUMAN antibody DUSP 1 antibody Dusp1 antibody HVH1 antibody MAP kinase phosphatase 1 antibody Mitogen-activated protein kinase phosphatase 1 antibody MKP-1 antibody MKP1 antibody Protein tyrosine phosphatase CL100 antibody Protein-tyrosine phosphatase CL100 antibody PTPN10 antibody Serine/threonine specific protein phosphatase antibody VH1 antibody
Abbreviation: MAP kinase phosphatase 1, MKP-1
Swiss Prot: P28562 Human, P28563 Mouse, Q64623 Rat
Cellular Locus: Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human DUSP1 aa 112-156 / 367.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, IP, FC, IF-Cell, IF-Tissue
Positive Control: Jurkat cell lysate, SK-Br-3 cell lysate, NIH/3T3 cell lysate, mouse liver tissue lysate, mouse kidney tissue lysate, rat liver tissue lysate, rat kidney tissue lysate, NIH/3T3, C6, human lung cancer tissue, mouse lung tissue, rat lung tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IHC-P: 1:1,000 ;FC: 1:1,000 ;IP: 1-2μg/sample ;IF-Cell: 1:100 ;IF-Tissue: 1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 39 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for DUSP1 Recombinant Rabbit Monoclonal Antibody [JJ0930]?

The catalog number for DUSP1 Recombinant Rabbit Monoclonal Antibody [JJ0930] is ET1701-82.

Is DUSP1 Recombinant Rabbit Monoclonal Antibody [JJ0930] in stock?

DUSP1 Recombinant Rabbit Monoclonal Antibody [JJ0930] is currently made to order / not held in immediate stock. Contact us for lead time.

What is DUSP1 Recombinant Rabbit Monoclonal Antibody [JJ0930] used for?

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.