Von Willebrand Factor Recombinant Rabbit Monoclonal Antibody [JJ09-34] — image 1 of 2

Product details

Von Willebrand Factor Recombinant Rabbit Monoclonal Antibody [JJ09-34]

Catalog number ET1701-87

Price for ET1701-87

Size / count 100 µL

About this product

Von Willebrand disease is a congenital bleeding disorder caused by defects in the von Willebrand factor protein (VWF). VWF is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets, and it is involved in the coagulation of blood at injury sites. VWF acts as a carrier protein for Factor VIII, a cofactor required for coagulation, and it promotes platelet adhesion and aggregation. Several factors are known to stimulate the binding of VWF to platelets, including glycoprotein 1b, ristocetin, botrocetin, collagen, sulphatides and heparin. Of the several domains contained within VWF, the A1, A2 and A3 domains have been shown to mediate this activation. VWF is thought to undergo a variety of posttranslational modifications that influence the affinity and availability for Factor VII, including cleavage of the propeptide and formation of N-terminal intersubunit disulfide bonds.

Specifications

Catalog number: ET1701-87
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Coagulation factor VIII antibody Coagulation factor VIII VWF antibody F8VWF antibody Factor VIII related antigen antibody von Willebrand antigen 2 antibody von Willebrand antigen II antibody Von Willebrand disease antibody VWD antibody vWF antibody VWF_HUMAN antibody
Abbreviation: vWF
Swiss Prot: P04275 Human, Q8CIZ8 Mouse
Cellular Locus: Secreted.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Recombinant protein within Human Von Willebrand Factor aa 1170-1320 / 2813.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: BEnd.3 cell lysate, human lung tissue lysate, mouse lung tissue lysate, mouse liver tissue lysate, human tonsil tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:5,000 ;IHC-P: 1:50-1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 309 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Von Willebrand Factor Recombinant Rabbit Monoclonal Antibody [JJ09-34]?

The catalog number for Von Willebrand Factor Recombinant Rabbit Monoclonal Antibody [JJ09-34] is ET1701-87.

What sizes are available for Von Willebrand Factor Recombinant Rabbit Monoclonal Antibody [JJ09-34]?

Von Willebrand Factor Recombinant Rabbit Monoclonal Antibody [JJ09-34] is available in the following size(s): 100 µL.

Is Von Willebrand Factor Recombinant Rabbit Monoclonal Antibody [JJ09-34] in stock?

Von Willebrand Factor Recombinant Rabbit Monoclonal Antibody [JJ09-34] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Von Willebrand Factor Recombinant Rabbit Monoclonal Antibody [JJ09-34] used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.