LAMP1 Recombinant Rabbit Monoclonal Antibody [JJ0940]

About this product

Lysosomal-associated membrane protein 1 (LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a (Cluster of Differentiation 107a), is a protein that in humans is encoded by the LAMP1 gene. The human LAMP1 gene is located on the long arm (q) of chromosome 13 at region 3, band 4 (13q34).Immunofluorescence staining of HeLa Cells with antibody to reveal lysosomal LAMP1 in red and vimentin containing intermediate filaments in green. Nuclear DNA is seen in blue. Antibodies and image courtesy EnCor Biotechnology Inc.Lysosomal-associated membrane protein 1 is a glycoprotein from a family of Lysosome-associated membrane glycoproteins.The LAMP-1 glycoprotein is a type I transmembrane protein which is expressed at high or medium levels in at least 76 different normal tissue cell types.It resides primarily across lysosomal membranes,and functions to provide selectins with carbohydrate ligands. CD107a has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells. and may also play a role in tumor cell differentiation and metastasis.

Specifications

Catalog number

ET1701-94

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

CD107 antigen like family member A antibody CD107 antigen-like family member A antibody CD107a antibody CD107a antigen antibody LAMP 1 antibody LAMP-1 antibody LAMP1 antibody LAMP1_HUMAN antibody LAMPA antibody LGP120 antibody lgpA antibody Lysosomal membrane glycoprotein 120KD antibody Lysosomal Associated Membrane Protein 1 antibody Lysosome associated membrane glycoprotein 1 antibody Lysosome-associated membrane glycoprotein 1 antibody Lysosome-associated membrane protein 1 antibody OTTHUMP00000040663 antibody

Abbreviation

LAMP-1, Lysosome-associated membrane protein 1, LAMP1

Swiss Prot

P11279 Human

Cellular Locus

Cell membrane, Endosome membrane, Lysosome membrane, Late endosome.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant protein within Human LAMP1 aa 84-206 / 417.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IF-Tissue

Positive Control

HeLa cell lysate, Jurkat cell lysate, HepG2 cell lysate, HUVEC cell lysate, human kidney tissue lysate, human kidney tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:5,000 ;IHC-P: 1:5,000 ;IF-Tissue: 1:200-1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 45 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes