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Product details

c-Fos Recombinant Rabbit Monoclonal Antibody [JJ0938]

Catalog number ET1701-95

Price for ET1701-95

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Size / count 100 µL

About this product

Protein c-Fos is a proto-oncogene that is the human homolog of the retroviral oncogene v-fos.[5] It is encoded in humans by the FOS gene. It was first discovered in rat fibroblasts as the transforming gene of the FBJ MSV (Finkel–Biskis–Jinkins murine osteogenic sarcoma virus) (Curran and Tech, 1982). It is a part of a bigger Fos family of transcription factors which includes c-Fos, FosB, Fra-1 and Fra-2.It has been mapped to chromosome region 14q21→q31. c-Fos encodes a 62 kDa protein, which forms heterodimer with c-jun (part of Jun family of transcription factors), resulting in the formation of AP-1 (Activator Protein-1) complex which binds DNA at AP-1 specific sites at the promoter and enhancer regions of target genes and converts extracellular signals into changes of gene expression.It plays an important role in many cellular functions and has been found to be overexpressed in a variety of cancers.

Specifications

Catalog number
ET1701-95
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Activator protein 1 antibody AP 1 antibody C FOS antibody Cellular oncogene c fos antibody Cellular oncogene fos antibody FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS) antibody FBJ murine osteosarcoma viral oncogene homolog antibody FBJ murine osteosarcoma viral v fos oncogene homolog antibody FBJ Osteosarcoma Virus antibody FOS antibody FOS protein antibody FOS_HUMAN antibody G0 G1 switch regulatory protein 7 antibody G0/G1 switch regulatory protein 7 antibody G0S7 antibody Oncogene FOS antibody p55 antibody proto oncogene c Fos antibody Proto oncogene protein c fos antibody Proto-oncogene c-Fos antibody v fos FBJ murine osteosarcoma viral oncogene homolog antibody
Abbreviation
FOS
Swiss Prot
P01100 Human, P01101 Mouse, P12841 Rat
Cellular Locus
Nucleus, Endoplasmic reticulum, Cytoplasm.
Host
Rabbit
Species Reactivity
Mouse, Human, Rat
Immunogen
Synthetic peptide within Human c-Fos aa 231-268 / 380.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, FC, IF-Cell
Positive Control
Human placenta tissue, NIH/3T3, NIH/3T3 cell lysate, MCF-7 cell lysate, HeLa serum starved for 40 hours then treated with 20% FBS for 2 hours.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100 ;IF-Cell:1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
41 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for c-Fos Recombinant Rabbit Monoclonal Antibody [JJ0938]?

The catalog number for c-Fos Recombinant Rabbit Monoclonal Antibody [JJ0938] is ET1701-95.

What sizes are available for c-Fos Recombinant Rabbit Monoclonal Antibody [JJ0938]?

c-Fos Recombinant Rabbit Monoclonal Antibody [JJ0938] is available in the following size(s): 100 µL.

Is c-Fos Recombinant Rabbit Monoclonal Antibody [JJ0938] in stock?

c-Fos Recombinant Rabbit Monoclonal Antibody [JJ0938] is currently made to order / not held in immediate stock. Contact us for lead time.

What is c-Fos Recombinant Rabbit Monoclonal Antibody [JJ0938] used for?

Protein c-Fos is a proto-oncogene that is the human homolog of the retroviral oncogene v-fos.[5] It is encoded in humans by the FOS gene. It was first discovered in rat fibroblasts as the transforming gene of the FBJ MSV (Finkel–Biskis–Jinkins murine osteogenic sarcoma virus) (Curran and Tech, 1982)

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

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