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Product details

Insulin degrading enzyme Recombinant Rabbit Monoclonal Antibody [JJ0949]

Catalog number ET1701-97

Price for ET1701-97

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Size / count 100 µL

About this product

Insulin degrading enzyme (IDE), also known as insulinase, insulin protease or insulysin, cleaves the peptide hormone insulin with consequences for insulin response and resistance. IDE is a highly conserved thiol metalloprotease with ubiquitous expression including the brain. Since its discovery, IDE has been shown to degrade a variety of bioactive peptides. Recently the finding that IDE clears intracellular and extracellular amyloid products has spurred research into the link between IDE function and human neurodegenerative disease such as Alzheimer’s.

Specifications

Catalog number
ET1701-97
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Abeta-degrading protease antibody FLJ35968 antibody Ide antibody IDE_HUMAN antibody Insulin protease antibody Insulin-degrading enzyme antibody Insulinase antibody Insulysin antibody OTTHUMP00000020097 antibody
Abbreviation
Insulinase, IDE
Swiss Prot
P14735 Human, Q9JHR7 Mouse, P35559 Rat
Cellular Locus
Cytoplasm, Cell membrane, Secreted.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Zebrafish
Immunogen
Recombinant protein within Human Insulin degrading enzyme aa 1-106 / 1019.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
Zebrafish tissue lysate, Hela cell lysate, K562 cell lysate, human liver carcinoma tissue, human colon carcinoma tissue, human stomach carcinoma tissue, mouse colon tissue, hybrid fish (crucian-carp) heart tissue lysates.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
118 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Insulin degrading enzyme Recombinant Rabbit Monoclonal Antibody [JJ0949]?

The catalog number for Insulin degrading enzyme Recombinant Rabbit Monoclonal Antibody [JJ0949] is ET1701-97.

What sizes are available for Insulin degrading enzyme Recombinant Rabbit Monoclonal Antibody [JJ0949]?

Insulin degrading enzyme Recombinant Rabbit Monoclonal Antibody [JJ0949] is available in the following size(s): 100 µL.

Is Insulin degrading enzyme Recombinant Rabbit Monoclonal Antibody [JJ0949] in stock?

Insulin degrading enzyme Recombinant Rabbit Monoclonal Antibody [JJ0949] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Insulin degrading enzyme Recombinant Rabbit Monoclonal Antibody [JJ0949] used for?

Insulin degrading enzyme (IDE), also known as insulinase, insulin protease or insulysin, cleaves the peptide hormone insulin with consequences for insulin response and resistance. IDE is a highly conserved thiol metalloprotease with ubiquitous expression including the brain. Since its discovery, IDE

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

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