Mitofusin 1 Recombinant Rabbit Monoclonal Antibody [JF0954] — image 1 of 2

Product details

Mitofusin 1 Recombinant Rabbit Monoclonal Antibody [JF0954]

Catalog number ET1702-01

Price for ET1702-01

Size / count 100 µL

About this product

Mitofusin 1 (Mfn1) and mitofusin 2 (Mfn2) are homologs for the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins and are mediators of mitochondrial fusion. A GTPase domain is required for Mfn protein function but the molecular mechanisms of the GTPase-dependent reaction as well as the functional division of the two Mfn proteins are unknown. They are essential for embryonic development and may play a role in the pathobiology of obesity. Although the Mfn1 and Mfn2 genes are broadly expressed, they show different levels of expression in different tissues. Two Mfn1 transcripts are elevated in heart, while Mfn2 mRNA is abundantly expressed in heart and muscle tissue but present only at low levels in many other tissues. Mfn1 localizes to mitochondria and participates in at least two different high molecular weight protein complexes in a GTP-dependent manner. Purified recombinant Mfn1 exhibited approximately eightfold higher GTPase activity than Mfn2.

Specifications

Catalog number: ET1702-01
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Fzo homolog antibody Hfzo1 antibody Hfzo2 antibody MFN 1 antibody Mfn1 antibody MFN1_HUMAN antibody Mitochondrial transmembrane GTPase Fzo 1 antibody Mitochondrial transmembrane GTPase FZO 2 antibody Mitochondrial transmembrane GTPase FZO1B antibody Mitofusin 1 antibody Mitofusin-1 antibody Mitofusin1 antibody MS996 antibody Putative transmembrane GTPase antibody Transmembrane GTPase MFN1 antibody
Abbreviation: MFN1
Swiss Prot: Q8IWA4 Human
Cellular Locus: Mitochondrion outer membrane, Cytoplasm.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within Human Mitofusin 1 aa 491-620 / 741.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IP, FC
Positive Control: K562 cell lysates, 293.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:2,000 ;FC: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 84 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Mitofusin 1 Recombinant Rabbit Monoclonal Antibody [JF0954]?

The catalog number for Mitofusin 1 Recombinant Rabbit Monoclonal Antibody [JF0954] is ET1702-01.

What sizes are available for Mitofusin 1 Recombinant Rabbit Monoclonal Antibody [JF0954]?

Mitofusin 1 Recombinant Rabbit Monoclonal Antibody [JF0954] is available in the following size(s): 100 µL.

Is Mitofusin 1 Recombinant Rabbit Monoclonal Antibody [JF0954] in stock?

Mitofusin 1 Recombinant Rabbit Monoclonal Antibody [JF0954] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Mitofusin 1 Recombinant Rabbit Monoclonal Antibody [JF0954] used for?

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.