Src Recombinant Rabbit Monoclonal Antibody [JF0947]

About this product

The major translational products of the Src gene family are membrane-associated tyrosine protein kinases that lack transmembrane and external amino acid sequences. By virtue of their common structural motifs, the Src family is composed of nine members in vertebrates, including c-Src, c-Yes, Fgr, Yrk, Fyn, Lyn, Hck, Lck and Blk. Src family kinases, which contain an amino-terminal cell membrane anchor followed by SH3 and SH2 domains, transduce signals that are involved in the control of a variety of cellular processes, including proliferation, differentiation, motility and adhesion. Src family members are normally maintained in an inactive state and can be activated transiently during cellular events such as mitosis. Different subcellular locations of Src family kinases may be important for the regulation of specific cellular processes, such as mitogenesis, cytoskeletal organization and membrane trafficking. c-Src (also designated pp60Src, Src p60 and proto-oncogene tyrosine protein kinase Src) is expressed in a broad range of tissue and cell types, although the highest levels of c-Src are detected in neuronal tissues and platelets. c-Src may play a role in events associated with both neuronal differentiation and maintenance of mature neuronal cell functions.

Specifications

Catalog number

ET1702-03

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

ASV antibody Avian sarcoma virus antibody c SRC antibody CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA antibody cSrc antibody EC 2.7.10.2 antibody Neuronal CSRC tyrosine specific protein kinase antibody Neuronal SRC antibody Oncogene SRC antibody OTTHUMP00000174476 antibody OTTHUMP00000174477 antibody p60 Src antibody p60-Src antibody p60Src antibody pp60c src antibody pp60c-src antibody pp60csrc antibody Proto oncogene tyrosine protein kinase Src antibody Proto-oncogene c-Src antibody Proto-oncogene tyrosine-protein kinase Src antibody Protooncogene SRC antibody Protooncogene SRC Rous sarcoma antibody Src antibody SRC Oncogene antibody SRC proto oncogene non receptor tyrosine kinase antibody SRC_HUMAN antibody SRC1 antibody Tyrosine kinase pp60c src antibody Tyrosine protein kinase SRC 1 antibody Tyrosine protein kinase SRC1 antibody v src avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog antibody V src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog (avian) antibody v src sarcoma (Schmidt Ruppin A 2) viral oncogene homolog avian antibody

Abbreviation

p60-Src, SRC

Swiss Prot

P12931 Human, P05480 Mouse, Q9WUD9 Rat

Cellular Locus

Cell membrane, Mitochondrion inner membrane, Nucleus, Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within human Src aa 20-60.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, IP, FC

Positive Control

SK-OV-3 cell lysate, A549 cell lysate, NIH/3T3 cell lysate, 4T1 cell lysate, PC-12 cell lysate, C6 cell lysate, COS-1 cell lysate, SK-OV-3, NIH/3T3, PC-12, human kidney tissue, mouse kidney tissue, rat kidney tissue, SK-OV-3 Y.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:5,000 ;IF-Cell: 1:100-1:500 ;IF-Tissue: 1:100-1:500 ;IHC-P: 1:20-1:1,000 ;IP: 1/2,000 ;FC: 1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 60 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes