67kDa Laminin Receptor Recombinant Rabbit Monoclonal Antibody [JF0955]

About this product

Laminin receptor (Laminin-R) has a heterodimeric structure similar to that of receptors for other extracellular matrix proteins such as Fibronectin and Vitronectin. Incorporation of Laminin-R into lysosomal membranes makes it possible for lysosomes to attach to surfaces coated with Laminin. This and other properties identify Laminin-R as a member of the integrin family of cell adhesion receptors. The Laminin-R precursor is a polypeptide whose expression is consistently upregulated in aggressive carcinoma. The precursor, which is also identified as p40 ribosome-associated protein, appears to be a multifunctional protein involved in the translational machinery. Laminin-R (also known as colon carcinoma laminin-binding protein) and is found at nine-fold higher levels in colon carcinoma than in adjacent normal colonic epithelium. Additionally, the level of the Laminin-R is higher in the lung cancer cell line than in the lung cell line.

Specifications

Catalog number

ET1702-05

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

34/67 kDa laminin receptor antibody 37 kDa laminin receptor precursor antibody 37/67 kDa laminin receptor antibody 37LRP antibody 40S ribosomal protein SA antibody 67 kDa laminin receptor antibody 67LR antibody Colon carcinoma laminin binding protein antibody Colon carcinoma laminin-binding protein antibody LAMBR antibody Laminin receptor 1 antibody Laminin-binding protein precursor p40 antibody LAMR 1 antibody LamR antibody LAMR1 antibody LBP antibody LBP/p40 antibody LRP antibody LRP/LR antibody Multidrug resistance associated protein MGr1 Ag antibody Multidrug resistance associated protein MGr1Ag antibody Multidrug resistance-associated protein MGr1-Ag antibody NEM/1CHD4 antibody p40 antibody Ribosomal Protein SA antibody rpsA antibody RSSA_HUMAN antibody SA antibody

Abbreviation

37LRP, LRP/LR, 67LR, LamR, LBP/p40, RPSA

Swiss Prot

P08865 Human, P14206 Mouse, P38983 Rat

Cellular Locus

Cell membrane, Nucleus, Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human 67kDa Laminin Receptor aa250-295 / 295.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, IP, FC

Positive Control

K562 cell lysate, HepG2 cell lysate, A431 cell lysate, Hela, MCF-7, HepG2, RH-35, mouse brain tissue, mouse kidney tissue, human stomach carcinoma tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:2,000;IF-Cell: 1:100-1:500;IF-Tissue: 1:100-1:500;IHC-P: 1:50-1:200;FC: 1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 33 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes