ABL2 Recombinant Rabbit Monoclonal Antibody [JF0951]

About this product

The Abl oncogene was initially identified as the viral transforming gene of Abelson murine leukemia virus (A-MuLV). The major translational product of c-Abl has been identified as a protein with tyrosine kinase activity and an SH2 domain. The Abl oncogene is implicated in several human leukemias including chronic myelocytic leukemia (CML), in which it undergoes a (9;22) chromosomal translocation and produces the Philadelphia (Ph1) chromosome. The molecular consequence of this translocation is the generation of a chimeric Bcr/c-Abl mRNA encoding activated Abl protein tyrosine kinase. The related protein tyrosine kinase Arg, also designated Abl2, contains an SH2 and an SH3 domain. Arg has been shown to interact with and to phosphorylate c-Crk.

Specifications

Catalog number

ET1702-07

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Abelson murine leukemia viral oncogene homolog 2 antibody Abelson related gene protein antibody Abelson tyrosine-protein kinase 2 antibody Abelson-related gene protein antibody ABL2 antibody ABL2_HUMAN antibody ABLL antibody ARG antibody Tyrosine kinase ARG antibody Tyrosine protein kinase ABL2 antibody Tyrosine-protein kinase ARG antibody v abl Abelson murine leukemia viral oncogene homolog 2 antibody

Abbreviation

ABL2

Swiss Prot

P42684 Human, Q4JIM5 Mouse

Cellular Locus

Cytoplasm, cytoskeleton.

Host

Rabbit

Species Reactivity

Human, Rat, Mouse

Immunogen

Synthetic peptide within Human ABL2 aa 502-552 / 1182.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, FC

Positive Control

Hela cell lysate, PC-12 cell lysate, Jurkat cell lysate, Raji.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:2,000 ;FC: 1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 128 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes