Glucocorticoid Receptor Recombinant Rabbit Monoclonal Antibody [JF0952] — image 1 of 3

Product details

Glucocorticoid Receptor Recombinant Rabbit Monoclonal Antibody [JF0952]

Catalog number ET1702-11

Price for ET1702-11

Size / count 100 µL

About this product

The glucocorticoid receptor (GR) is a ubiquitously expressed transcription factor that mediates the effects of glucocorticoids. The most abundant isoform is GR α. GR induces or represses the expression of genes in response to glucocorticoids, mediating such processes as apoptosis, cell growth and differentiation. A significant class of genes suppressed by GR is controlled by the transcription factor AP-1. GR has also been shown to be the limiting factor in the induction of gene expression by glucocorticoids. It has been revealed that GR forms a complex with HSP 90, rendering the non-ligand bound receptor transcriptionally inactive. More importantly, mutant GRs lacking the signaling domain remain constitutively active.

Specifications

Catalog number: ET1702-11
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: GCCR antibody GCR antibody GCR_HUMAN antibody GCRST antibody glucocorticoid nuclear receptor variant 1 antibody Glucocorticoid receptor antibody GR antibody GRL antibody Grl1 antibody nr3c1 antibody Nuclear receptor subfamily 3 group C member 1 antibody nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) antibody
Abbreviation: GR, NR3C1
Swiss Prot: P04150 Human, P06537 Mouse, P06536 Rat
Cellular Locus: Cytoplasm, Nucleus, Mitochondrion.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat, Zebrafish
Immunogen: Recombinant protein within Human Glucocorticoid Receptor aa 2-220 / 777.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, FC
Positive Control: HeLa cell lysate, A549 cell lysate, NIH/3T3 cell lysate, C6 cell lysate, Zebrafish tissue lysate, C6, HeLa, hybrid fish (crucian-carp) heart tissue lysates.
Concentration: 1 mg/mL
Dilution: WB: 1:2,000 ;IF-Cell: 1:100 ;FC: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 86 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Glucocorticoid Receptor Recombinant Rabbit Monoclonal Antibody [JF0952]?

The catalog number for Glucocorticoid Receptor Recombinant Rabbit Monoclonal Antibody [JF0952] is ET1702-11.

What sizes are available for Glucocorticoid Receptor Recombinant Rabbit Monoclonal Antibody [JF0952]?

Glucocorticoid Receptor Recombinant Rabbit Monoclonal Antibody [JF0952] is available in the following size(s): 100 µL.

Is Glucocorticoid Receptor Recombinant Rabbit Monoclonal Antibody [JF0952] in stock?

Glucocorticoid Receptor Recombinant Rabbit Monoclonal Antibody [JF0952] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Glucocorticoid Receptor Recombinant Rabbit Monoclonal Antibody [JF0952] used for?

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.