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Product details

Myelin Basic Protein Recombinant Rabbit Monoclonal Antibody [JF0943]

Catalog number ET1702-15

Price for ET1702-15

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Size / count 100 µL

About this product

Myelin basic protein (MBP) is the major extrinsic membrane protein of central nervous system myelin. MBP phosphorylation at Threonine 125 is a complex regulatory process that modulates the contribution of MBP to the stability of the myelin sheath. Mitogen-activated protein kinases modulate MBP phosphorylation during myelinogenesis and in the demyelinating disease multiple sclerosis. MBP phosphorylation is regulated by high-frequency stimulation but not low-frequency stimulation of the alveus, the myelinated output fibers of the hippocampus. It is proposed that during periods of increased neuronal activity, calcium activates axonal nitric oxide synthase, which generates the intercellular messengers nitric oxide and superoxide and regulates the phosphorylation state of MBP by MAPK.

Specifications

Catalog number
ET1702-15
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
GDB antibody Golli MBP antibody Golli MBP; myelin basic protein antibody Hemopoietic MBP antibody HMBPR antibody HUGO antibody MBP antibody MBP_CAVPO antibody MBP_HUMAN antibody MGC99675 antibody MLD antibody Myelin A1 protein antibody Myelin A1 Protein, basic antibody Myelin basic protein antibody Myelin Deficient antibody Myelin membrane encephalitogenic protein antibody OTTHUMP00000163776 antibody OTTHUMP00000174387 antibody OTTHUMP00000174388 antibody SHI antibody Shiverer antibody SP antibody
Abbreviation
MBP
Swiss Prot
P02686 Human, P04370 Mouse, P02688 Rat
Cellular Locus
Myelin membrane, Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human Myelin Basic Protein aa 121-304 / 304.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Tissue, IHC-Fr
Positive Control
Rat brain tissue lysate, Mouse brain tissue lysate, human brain tissue, mouse brain tissue, rat brain tissue, mouse cerebral cortex tissue, mouse hippocampus tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:1,000 ;IF-Tissue: 1:200 ;IHC-Fr: 1:200-1:500
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 33 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Myelin Basic Protein Recombinant Rabbit Monoclonal Antibody [JF0943]?

The catalog number for Myelin Basic Protein Recombinant Rabbit Monoclonal Antibody [JF0943] is ET1702-15.

What sizes are available for Myelin Basic Protein Recombinant Rabbit Monoclonal Antibody [JF0943]?

Myelin Basic Protein Recombinant Rabbit Monoclonal Antibody [JF0943] is available in the following size(s): 100 µL.

Is Myelin Basic Protein Recombinant Rabbit Monoclonal Antibody [JF0943] in stock?

Myelin Basic Protein Recombinant Rabbit Monoclonal Antibody [JF0943] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Myelin Basic Protein Recombinant Rabbit Monoclonal Antibody [JF0943] used for?

Myelin basic protein (MBP) is the major extrinsic membrane protein of central nervous system myelin. MBP phosphorylation at Threonine 125 is a complex regulatory process that modulates the contribution of MBP to the stability of the myelin sheath. Mitogen-activated protein kinases modulate MBP phosp

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

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