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Product details

Telomerase reverse transcriptase Recombinant Rabbit Monoclonal Antibody [JF0586]

Catalog number ET1702-22

Price for ET1702-22

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Size / count 100 µL

About this product

Telomerase is an RNA-dependent DNA polymerase that catalyzes the addition of telomeric repeat sequences to chromosome ends. In most human somatic cells, telomerase activity is undetectable, and telomeres shorten with successive cell divisions. However, telomerase activity is detectable in immortal cells and in many human tumors. Two candidate mammalian telomerase proteins have been cloned. Human TP1 (for telomerase-associated protein 1), also designated TLP1 in rat (for telomerase protein component 1), is homologous to the Tetrahymena p80 telomerase protein and has been shown to interact with mammalian telomerase RNA. Human TERT (for telomerase reverse transcriptase), also designated hEST2 (for ever shorter telomeres), is homologous to the p123 telomerase protein from Euplotes and to the yeast Est2 protein. Expression of TERT mRNA has been shown to correlate with telomerase activity in various cell lines.

Specifications

Catalog number
ET1702-22
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
CMM9 antibody DKCA2 antibody DKCB4 antibody EST2 antibody HEST2 antibody htert antibody hTRT antibody PFBMFT1 antibody TCS1 antibody Telomerase associated protein 2 antibody Telomerase catalytic subunit antibody Telomerase reverse transcriptase antibody Telomerase-associated protein 2 antibody Telomere Reverse Transcriptase antibody TERT antibody TERT_HUMAN antibody TP2 antibody TRT antibody
Abbreviation
TP2, TERT
Swiss Prot
O14746 Human
Cellular Locus
Nucleus, Chromosome, Cytoplasm.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within human Telomerase reverse transcriptase aa 1090-1132/1132.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, FC
Positive Control
HeLa cell lysates, HeLa.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
127/120/90/89 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Telomerase reverse transcriptase Recombinant Rabbit Monoclonal Antibody [JF0586]?

The catalog number for Telomerase reverse transcriptase Recombinant Rabbit Monoclonal Antibody [JF0586] is ET1702-22.

What sizes are available for Telomerase reverse transcriptase Recombinant Rabbit Monoclonal Antibody [JF0586]?

Telomerase reverse transcriptase Recombinant Rabbit Monoclonal Antibody [JF0586] is available in the following size(s): 100 µL.

Is Telomerase reverse transcriptase Recombinant Rabbit Monoclonal Antibody [JF0586] in stock?

Telomerase reverse transcriptase Recombinant Rabbit Monoclonal Antibody [JF0586] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Telomerase reverse transcriptase Recombinant Rabbit Monoclonal Antibody [JF0586] used for?

Telomerase is an RNA-dependent DNA polymerase that catalyzes the addition of telomeric repeat sequences to chromosome ends. In most human somatic cells, telomerase activity is undetectable, and telomeres shorten with successive cell divisions. However, telomerase activity is detectable in immortal c

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

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