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Product details

PDIA6 Recombinant Rabbit Monoclonal Antibody [JF0974]

Catalog number ET1702-26

Price for ET1702-26

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Size / count 100 µL

About this product

Endoplasmic reticulum proteins (ERps) are widely expressed proteins that localize to the ER and may act as proteases, protein disulfide isomerases, thiol-disulfide oxidases or phospholipases. ERp5, also known as PDIA6 (protein disulfide isomerase family A, member 6) or TXNDC7 is a 440 amino acid protein that contains two thioredoxin domains and belongs to the protein disulfide isomerase family. Localized to the melanosome, as well as to the lumen of the endoplasmic reticulum, ERp5 functions to catalyze the rearrangement of disulfide bonds in a variety of different proteins. Via its catalytic activity, ERp5 is able to reduce the disulfide bond that binds MICA to tumor cells, thereby releasing MICA and reducing the rate of tumor expansion. Multiple isoforms of ERp5 exist due to alternative splicing events.

Specifications

Catalog number
ET1702-26
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Endoplasmic reticulum protein 5 antibody ER protein 5 antibody ERp5 antibody P5 antibody Pdia6 antibody PDIA6_HUMAN antibody Protein disulfide isomerase A6 antibody Protein disulfide isomerase associated 6 antibody Protein disulfide isomerase family A member 6 antibody Protein disulfide isomerase P5 antibody Protein disulfide isomerase related protein antibody Protein disulfide-isomerase A6 antibody Thioredoxin domain containing 7 (protein disulfide isomerase) antibody Thioredoxin domain containing protein 7 antibody Thioredoxin domain-containing protein 7 antibody TXNDC7 antibody
Abbreviation
ER protein 5, ERp5, PDIA6
Swiss Prot
Q15084 Human, Q922R8 Mouse, Q63081 Rat
Cellular Locus
Endoplasmic reticulum lumen, Cell membrane, Melanosome.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within PDIA6 aa 1-108 / 440.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, FC
Positive Control
HepG2 cell lysate, K562 cell lysate, Hela, HepG2, NIH/3T3.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
48 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for PDIA6 Recombinant Rabbit Monoclonal Antibody [JF0974]?

The catalog number for PDIA6 Recombinant Rabbit Monoclonal Antibody [JF0974] is ET1702-26.

What sizes are available for PDIA6 Recombinant Rabbit Monoclonal Antibody [JF0974]?

PDIA6 Recombinant Rabbit Monoclonal Antibody [JF0974] is available in the following size(s): 100 µL.

Is PDIA6 Recombinant Rabbit Monoclonal Antibody [JF0974] in stock?

PDIA6 Recombinant Rabbit Monoclonal Antibody [JF0974] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PDIA6 Recombinant Rabbit Monoclonal Antibody [JF0974] used for?

Endoplasmic reticulum proteins (ERps) are widely expressed proteins that localize to the ER and may act as proteases, protein disulfide isomerases, thiol-disulfide oxidases or phospholipases. ERp5, also known as PDIA6 (protein disulfide isomerase family A, member 6) or TXNDC7 is a 440 amino acid pro

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

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