RAGE Recombinant Rabbit Monoclonal Antibody [JF0975] — image 1 of 3

Product details

RAGE Recombinant Rabbit Monoclonal Antibody [JF0975]

Catalog number ET1702-27

Price for ET1702-27

Size / count 100 µL

About this product

Advanced glycosylation end products of proteins (AGEs) are nonenzymatically glycosylated proteins that are associated with a variety of conditions, including diabetes and other vascular disorders, as well as amyloidosis. These proteins regulate cellular functions via specific cell surface acceptor molecules, such as RAGE (receptor for advanced glycosylation end products). RAGE is a type 1 membrane protein that is found on the surface of endothelial cells, mononuclear phagocytes and vascular smooth muscle cells. Binding of AGEs to RAGE results in the induction of cellular oxidant stress and activation of the transcription factor NFkB. Evidence suggests that the induction of oxidant stress results in the activation of an intracellular cascade involving p21 ras and MAP kinase, which leads to activation of transcription.

Specifications

Catalog number: ET1702-27
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Advanced glycosylation end product-specific receptor antibody Ager antibody MGC2235 antibody RAGE_HUMAN antibody Receptor for advanced glycosylation end products antibody
Abbreviation: AGER
Swiss Prot: Q15109 Human, Q62151 Mouse, Q63495 Rat
Cellular Locus: Cell membrane, Secreted.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within human RAGE aa 350-390.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, IF-Tissue, mIHC
Positive Control: Mouse lung tissue lysate, rat lung tissue lysate, rat lung tissue, mouse lung tissue, human lung tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:2,000-1:5,000 ;IHC-P: 1:200-1:1,000 ;IF-Tissue: 1:100 ;mIHC: 1:3,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 43 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for RAGE Recombinant Rabbit Monoclonal Antibody [JF0975]?

The catalog number for RAGE Recombinant Rabbit Monoclonal Antibody [JF0975] is ET1702-27.

What sizes are available for RAGE Recombinant Rabbit Monoclonal Antibody [JF0975]?

RAGE Recombinant Rabbit Monoclonal Antibody [JF0975] is available in the following size(s): 100 µL.

Is RAGE Recombinant Rabbit Monoclonal Antibody [JF0975] in stock?

RAGE Recombinant Rabbit Monoclonal Antibody [JF0975] is currently made to order / not held in immediate stock. Contact us for lead time.

What is RAGE Recombinant Rabbit Monoclonal Antibody [JF0975] used for?

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.