S100 alpha 6 Recombinant Rabbit Monoclonal Antibody [JF0976]

About this product

Calcyclin, also known as Prolactin receptor-associated protein (PRA), growth factor-inducible protein 2A9, S-100 calcium-binding protein A6 (S-100A6) or MLN 4, is a homodimeric member of the S-100 calcium-binding protein family whose expression is upregulated in proliferating and differentiating cells. Calcyclin is inducible by growth factors and overexpressed in acute myeloid leukemias. It is expressed in a cell-specific manner in subpopulations of neurons and astrocytes and in epithelial cells and fibroblasts. Calcyclin is a specific target of S-100B protein in vivo. The binding of Calcyclin to S-100B is stabilized by S-100B-bound calcium and zinc. Calcyclin associates with both Annexin XI and CacyBP (calcyclin-binding protein). It functions to activate several processes along the calcium signal transduction pathway including the regulation of cell growth, proliferation, secretion and exocytosis.

Specifications

Catalog number

ET1702-28

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

2A9 antibody 5B10 antibody CABP antibody CACY antibody Calcyclin antibody Growth factor inducible protein 2A9 antibody Growth factor-inducible protein 2A9 antibody MLN 4 antibody MLN4 antibody OTTHUMP00000015472 antibody OTTHUMP00000015473 antibody PRA antibody PRAGrowth factor inducible protein 2A9 antibody Prolactin receptor associated protein antibody Prolactin receptor-associated protein antibody Protein S100 A6 antibody Protein S100-A6 antibody S100 A6 antibody S100 calcium binding protein A6 (calcyclin) antibody S100 calcium binding protein A6 antibody S100 calcium-binding protein A6 antibody S100A6 antibody S10A6_HUMAN antibody

Abbreviation

PRA, S100A6

Swiss Prot

P06703 Human, P14069 Mouse, P05964 Rat

Cellular Locus

Nucleus envelope, Cytoplasm, Cell membrane.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant full length protein of Human S100 alpha 6 aa 1-90 / 90.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, IP, FC

Positive Control

HeLa cell lysate, A549 cell lysate, Neuro-2a cell lysate, C6 cell lysate, mouse lung tissue lysate, C6, human kidney tissue, human stomach carcinoma tissue, human colon carcinoma tissue, mouse brain tissue, mouse kidney tissue, rat kidney tissue.

Concentration

1 mg/mL

Dilution

WB: 1:2,000-1:5,000 ;IF-Cell: 1:100-1:500 ;IF-Tissue: 1:100-1:500 ;IHC-P: 1:50-1:1,000 ;FC: 1:50-1:100 ;IP: Use at an assay dependent concentration.

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 10 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes