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Product details

LYVE1 Recombinant Rabbit Monoclonal Antibody [JF0979]

Catalog number ET1702-29

Discontinued

Price for ET1702-29

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Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

Lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1) is expressed on the cell surface as a protein that is reduced by glycosidase treatment. LYVE-1 is abundant in spleen, lymph node, heart, lung and fetal liver, and is less abundant in appendix, bone marrow, placenta, muscle and adult liver. Expression of LYVE-1 is largely restricted to endothelial cells lining lymphatic vessels and splenic sinusoidal endothelial cells. LYVE-1 binds to both soluble and immobilized hyaluronan (HA) with greater specificity than HCAM. Like HCAM, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike HCAM, the LYVE-1 molecule co-localizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves. LYVE-1 is used as a marker to study tumor lymphangiogenesis, which is an important area of investigation.

Specifications

Catalog number
ET1702-29
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
Yes
CAS Number
9000-83-3
Product Name Alternative
Cell surface retention sequence-binding protein 1 antibody CRSBP 1 antibody CRSBP-1 antibody CRSBP1 antibody extracellular link domain containing 1 antibody extracellular link domain-containing 1 antibody Extracellular link domain-containing protein 1 antibody HAR antibody Hyaluronic acid receptor antibody Lymphatic endothelium specific hyaluronan receptor antibody lymphatic vessel endothelial hyaluronan receptor 1 antibody Lymphatic vessel endothelial hyaluronic acid receptor 1 antibody LYVE 1 antibody LYVE-1 antibody LYVE1 antibody LYVE1_HUMAN antibody XLKD1 antibody
Abbreviation
LYVE-1, CRSBP-1, LYVE1
Swiss Prot
Q9Y5Y7 Human
Cellular Locus
Membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human LYVE1 aa 36-72 / 322.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, FC
Positive Control
MCF-7 cell lysate, SW480 cell lysate, A431 cell lysate, HUVEC cell lysate, A431, HUVEC, SW480.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 35 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for LYVE1 Recombinant Rabbit Monoclonal Antibody [JF0979]?

The catalog number for LYVE1 Recombinant Rabbit Monoclonal Antibody [JF0979] is ET1702-29.

Is LYVE1 Recombinant Rabbit Monoclonal Antibody [JF0979] in stock?

LYVE1 Recombinant Rabbit Monoclonal Antibody [JF0979] is currently made to order / not held in immediate stock. Contact us for lead time.

What is LYVE1 Recombinant Rabbit Monoclonal Antibody [JF0979] used for?

Lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1) is expressed on the cell surface as a protein that is reduced by glycosidase treatment. LYVE-1 is abundant in spleen, lymph node, heart, lung and fetal liver, and is less abundant in appendix, bone marrow, placenta, muscle and adult liver.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

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