Product details
Catalog number ET1702-30
Price for ET1702-30
Size / count 100 µL
The spectrin gene family encodes a diverse group of cytoskeletal proteins that include spectrins, dystrophins and α-actinins. There are four tissue-specific α-actinins, namely α-actinin-1, α-actinin-2, α-actinin-3 and α-actinin-4, which are localized to muscle and non-muscle cells, including skeletal, cardiac and smooth muscle cells, as well as within the cytoskeleton. Each α-actinin protein contains one Actin-binding domain, two calponin-homology domains, two EF-hand domains and four spectrin repeats, through which they function as bundling proteins that can cross-link F-Actin, thus anchoring Actin to a variety of intracellular structures. Defects in the gene encoding α-actinin-4 are the cause of focal segmental glomerulosclerosis 1 (FSGS1), a common renal lesion characterized by decreasing kidney function and, ultimately, renal failure.
The catalog number for Alpha Actinin 2 Recombinant Rabbit Monoclonal Antibody [JF0980] is ET1702-30.
Alpha Actinin 2 Recombinant Rabbit Monoclonal Antibody [JF0980] is available in the following size(s): 100 µL.
Alpha Actinin 2 Recombinant Rabbit Monoclonal Antibody [JF0980] is currently made to order / not held in immediate stock. Contact us for lead time.
The spectrin gene family encodes a diverse group of cytoskeletal proteins that include spectrins, dystrophins and α-actinins. There are four tissue-specific α-actinins, namely α-actinin-1, α-actinin-2, α-actinin-3 and α-actinin-4, which are localized to muscle and non-muscle cells, including skeleta
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