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Product details

Alpha Actinin 2 Recombinant Rabbit Monoclonal Antibody [JF0980]

Catalog number ET1702-30

Price for ET1702-30

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Size / count 100 µL

About this product

The spectrin gene family encodes a diverse group of cytoskeletal proteins that include spectrins, dystrophins and α-actinins. There are four tissue-specific α-actinins, namely α-actinin-1, α-actinin-2, α-actinin-3 and α-actinin-4, which are localized to muscle and non-muscle cells, including skeletal, cardiac and smooth muscle cells, as well as within the cytoskeleton. Each α-actinin protein contains one Actin-binding domain, two calponin-homology domains, two EF-hand domains and four spectrin repeats, through which they function as bundling proteins that can cross-link F-Actin, thus anchoring Actin to a variety of intracellular structures. Defects in the gene encoding α-actinin-4 are the cause of focal segmental glomerulosclerosis 1 (FSGS1), a common renal lesion characterized by decreasing kidney function and, ultimately, renal failure.

Specifications

Catalog number
ET1702-30
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Actin binding protein antibody Actinin alpha 2 antibody ACTN 2 antibody ACTN2 antibody ACTN2_HUMAN antibody Alpha actinin 2 antibody Alpha actinin skeletal muscle antibody Alpha actinin skeletal muscle isoform 2 antibody Alpha-actinin skeletal muscle isoform 2 antibody Alpha-actinin-2 antibody CMD1AA antibody F actin cross linking protein antibody F-actin cross-linking protein antibody
Abbreviation
ACTN2
Swiss Prot
P35609 Human, Q9JI91 Mouse,
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human Alpha Actinin 2 aa 1-50/894.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IP
Positive Control
Human heart tissue lysates, rat skeletal muscle tissue, rat heart tissue, mouse skeletal muscle tissue, mouse heart tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
104 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Alpha Actinin 2 Recombinant Rabbit Monoclonal Antibody [JF0980]?

The catalog number for Alpha Actinin 2 Recombinant Rabbit Monoclonal Antibody [JF0980] is ET1702-30.

What sizes are available for Alpha Actinin 2 Recombinant Rabbit Monoclonal Antibody [JF0980]?

Alpha Actinin 2 Recombinant Rabbit Monoclonal Antibody [JF0980] is available in the following size(s): 100 µL.

Is Alpha Actinin 2 Recombinant Rabbit Monoclonal Antibody [JF0980] in stock?

Alpha Actinin 2 Recombinant Rabbit Monoclonal Antibody [JF0980] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Alpha Actinin 2 Recombinant Rabbit Monoclonal Antibody [JF0980] used for?

The spectrin gene family encodes a diverse group of cytoskeletal proteins that include spectrins, dystrophins and α-actinins. There are four tissue-specific α-actinins, namely α-actinin-1, α-actinin-2, α-actinin-3 and α-actinin-4, which are localized to muscle and non-muscle cells, including skeleta

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

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