gamma Catenin Recombinant Rabbit Monoclonal Antibody [JF0973]

About this product

The catenins, α, β and γ, are proteins which bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. α-catenin was initially described as an E-cadherin associated protein, and since has been shown to associate with other members of the cadherin family, such as N-cadherin and P-cadherin. β-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. β-catenin has also been found in complexes with the tumor suppressor protein APC. γ-catenin, also known as plakoglobin, binds with α-catenin and N-cadherin. It has been shown that the transmembrane phosphatase PTP? associates with catenin/cadherin complexes and may regulate complex signaling.

Specifications

Catalog number

ET1702-33

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

ARVD 12 antibody ARVD12 antibody Catenin (cadherin associated protein), gamma 80kDa antibody catenin (cadherin-associated protein) gamma (80kD) antibody Catenin gamma antibody CTNNG antibody Desmoplakin 3 antibody Desmoplakin III antibody Desmoplakin-3 antibody Desmoplakin3 antibody DesmoplakinIII antibody DP 3 antibody DP III antibody DP3 antibody DPIII antibody gamma catenin antibody Junction plakoglobin antibody JUP antibody OTTHUMP00000164732 antibody OTTHUMP00000164735 antibody OTTHUMP00000164738 antibody PDGB antibody PKGB antibody PLAK_HUMAN antibody PLAKOGLOBIN antibody

Abbreviation

JUP

Swiss Prot

P14923 Human, Q02257 Mouse, Q6P0K8 Rat

Cellular Locus

Cytoskeleton, adherens junction, desmosome, Membrane.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within Human gamma Catenin aa 10-116 / 745.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, FC

Positive Control

Hela cell lysate, human skin tissue lysate, Hela, MCF-7, A431, mouse stomach tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:2,000;IF-Cell: 1:100-1:500;IF-Tissue: 1:100-1:500;IHC-P: 1:50-1:200;FC: 1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

82 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes