Argonaute 2 Recombinant Rabbit Monoclonal Antibody [JF0992] — image 1 of 3

Product details

Argonaute 2 Recombinant Rabbit Monoclonal Antibody [JF0992]

Catalog number ET1702-39

Discontinued

Price for ET1702-39

Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

Eukaryotic translation initiation factor 2C (eIF2C) proteins (argonaute family) influence RNA interference (RNAi) as components of the RNA-inducible silencing complex (RISC) or microRNA (miRNA)-containing ribonucleoprotein particle (miRNP). Small RNAs, including small interfering RNAs (siRNAs) and miRNAs, can silence target genes through mechanisms that utilize RISC or miRNP particles. eIF2C1 (argonaute 1, AGO1, eIF2C, GERP95, Q99) and Dicer1 play a coordinated role in siRNA-mediated gene silencing. eIF2C2 (Slicer, argonaute 2, AGO2, Q10) is a RISC component that can concentrate in cytoplasmic processing bodies (P-bodies) and catalyze mRNA cleavage. Mammalian P-bodies contain mRNAs and have an association with miRNA-induced translational silencing and siRNA-induced mRNA degradation. Additional eIF2C proteins include eIF2C3 (argonaute 3, AGO3), eIF2C4 (argonaute 4, AGO4) and meIF2c5 (mouse argonaute 5).

Specifications

Catalog number: ET1702-39
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
CAS Number: 9000-83-3
Product Name Alternative: Ago 2 antibody AGO2_HUMAN antibody Argonaute 2 antibody argonaute 2, RISC catalytic component antibody Argonaute RISC catalytic component 2 antibody Argonaute2 antibody CTA-204B4.6 antibody dAgo2 antibody eIF 2C 2 antibody eIF-2C 2 antibody eIF2C 2 antibody Eif2c2 antibody Eukaryotic translation initiation factor 2C 2 antibody Eukaryotic translation initiation factor 2C subunit 2 antibody hAgo2 antibody MGC3183 antibody PAZ Piwi domain protein antibody PPD antibody Protein argonaute-2 antibody Protein slicer antibody Q10 antibody Slicer protein antibody
Abbreviation: Argonaute2, hAgo2, eIF-2C 2, eIF2C 2, PPD, AGO2, EIF2C2
Swiss Prot: Q9UKV8 Human, Q8CJG0 Mouse, Q9QZ81 Rat
Cellular Locus: Cytoplasm, Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human Argonaute 2 aa 361-404 / 859.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IHC-P, FC, IP
Positive Control: HCT 116 cell lysate, HeLa cell lysate, HCT 116, RAW264.7, C6, mouse kidney tissue, mouse stomach tissue, human liver tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:2,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:1,000-1:4,000 ;FC: 1:50-1:100 ;IP: 1-2μg/sample
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 97 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Argonaute 2 Recombinant Rabbit Monoclonal Antibody [JF0992]?

The catalog number for Argonaute 2 Recombinant Rabbit Monoclonal Antibody [JF0992] is ET1702-39.

Is Argonaute 2 Recombinant Rabbit Monoclonal Antibody [JF0992] in stock?

Argonaute 2 Recombinant Rabbit Monoclonal Antibody [JF0992] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Argonaute 2 Recombinant Rabbit Monoclonal Antibody [JF0992] used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.