HMGCR Recombinant Rabbit Monoclonal Antibody [JF0981] — image 1 of 2

Product details

HMGCR Recombinant Rabbit Monoclonal Antibody [JF0981]

Catalog number ET1702-41

Price for ET1702-41

Size / count 100 µL

About this product

The human enzyme hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) limits the rate of cholesterol synthesis, a necessary process for cellular growth, in liver tissue. Phosphorylation of HMGCR inactivates the enzyme, which occurs via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from the product of the reductase reaction. Inhibitors of HMGCR (statins) exert anti-inflammatory effects and decrease the frequency of cardiovascular events by lowering plasma cholesterol. Additionally, intermediate products along the pathway catalyzed by HMGCR, which modulate signal transducing proteins such as Ras, provide possible ties between HMGCR regulation and new chemotherapeutic methods.

Specifications

Catalog number: ET1702-41
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: 3 hydroxy 3 methylglutaryl CoA reductase antibody 3 hydroxy 3 methylglutaryl Coenzyme A reductase antibody 3 hydroxymethylglutaryl CoA reductase antibody 3-hydroxy-3-methylglutaryl CoA reductase (NADPH) antibody 3-hydroxy-3-methylglutaryl-coenzyme A reductase antibody 3H3M antibody HMDH_HUMAN antibody HMG CoA reductase antibody HMG CoAR antibody HMG-CoA reductase antibody Hmgcr antibody Hydroxymethylglutaryl CoA reductase antibody LDLCQ3 antibody MGC103269 antibody Red antibody
Abbreviation: HMG-CoA reductase, HMGCR
Swiss Prot: P04035 Human, Q01237 Mouse, P51639 Rat
Cellular Locus: Endoplasmic reticulum membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human HMGCR aa 438-489 / 888.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IP, IHC-P
Positive Control: HeLa cell lysate, THP-1 cell lysate, HepG2 cell lysate, mouse testis tissue lysate, rat testis tissue lysate, human small intestine tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:5,000 ;IP: Use at an assay dependent concentration. ;IHC-P: 1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 97 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for HMGCR Recombinant Rabbit Monoclonal Antibody [JF0981]?

The catalog number for HMGCR Recombinant Rabbit Monoclonal Antibody [JF0981] is ET1702-41.

What sizes are available for HMGCR Recombinant Rabbit Monoclonal Antibody [JF0981]?

HMGCR Recombinant Rabbit Monoclonal Antibody [JF0981] is available in the following size(s): 100 µL.

Is HMGCR Recombinant Rabbit Monoclonal Antibody [JF0981] in stock?

HMGCR Recombinant Rabbit Monoclonal Antibody [JF0981] is currently made to order / not held in immediate stock. Contact us for lead time.

What is HMGCR Recombinant Rabbit Monoclonal Antibody [JF0981] used for?

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.