Product details
Catalog number ET1702-64
Price for ET1702-64
Size / count 100 µL
Midkine, or MK, is a heparin-binding molecule involved in the regulation of growth and differentiation during embryogenesis. MK expression is tightly regulated during embryonic development by steroid receptors of the retinoic acid superfamily. The mature human MK protein is 118 amino acids in length and contains five intrachain disulfide bonds. MK is a non-glycosylated protein that shows greater than 87% identity between human and mouse. The carboxy-terminus of MK contains the principle heparin-binding site and the molecule’s neurite-promoting sequences; both the amino- and carboxy-terminal sequences are required for the molecule’s neurotrophic properties. An association between overexpression of MK and colon adenocarcinoma has been shown in families suffering from familial polyposis. In addition, MK functions to enhance the activity of plasminogen activator (PA).
The catalog number for Midkine Recombinant Rabbit Monoclonal Antibody [JF096-5] is ET1702-64.
Midkine Recombinant Rabbit Monoclonal Antibody [JF096-5] is available in the following size(s): 100 µL.
Midkine Recombinant Rabbit Monoclonal Antibody [JF096-5] is currently made to order / not held in immediate stock. Contact us for lead time.
Midkine, or MK, is a heparin-binding molecule involved in the regulation of growth and differentiation during embryogenesis. MK expression is tightly regulated during embryonic development by steroid receptors of the retinoic acid superfamily. The mature human MK protein is 118 amino acids in length
A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.
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