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Product details

Neurofilament heavy polypeptide Recombinant Rabbit Monoclonal Antibody [JF99-07]

Catalog number ET1702-72

Price for ET1702-72

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Size / count 100 µL

About this product

Neurofilament-H (NF-H), for neurofilament heavy polypeptide, a member of the intermediate filament family, is a major component of neuronal cytoskeletons. Neurofilaments are dynamic structures; they contain phosphorylation sites for a large number of protein kinases, including protein kinase A, protein kinase C, cyclin-dependent kinase 5, extracellular signal regulated kinase, glycogen synthase kinase-3, and stress-activated protein kinase gamma. In addition to their role in the control of axon caliber, neurofilaments may affect other cytoskeletal elements, such as microtubules and Actin filaments. Changes in neurofilament phosphorylation or metabolism are frequently observed in neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), Parkinson's disease and Alzheimer's disease.

Specifications

Catalog number
ET1702-72
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
200 kDa neurofilament protein antibody CMT2CC antibody Nefh antibody Neurofilament heavy polypeptide 200kDa antibody Neurofilament heavy polypeptide antibody Neurofilament triplet H protein antibody NF H antibody NF-H antibody NFH antibody NFH_HUMAN antibody
Abbreviation
NF-H, NEFH
Swiss Prot
P12036 Human, P19246 Mouse, P16884 Rat
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human NEFH aa 690-740.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IHC-Fr, IF-Tissue
Positive Control
Mouse brain tissue lysate, Rat brain tissue lysate, Rat hippocampus tissue lysate, human cerebellum tissue, mouse cerebellum tissue, rat cerebellum tissue.
Concentration
1 mg/mL
Dilution
WB: 1:2,000 ;IHC-P: 1:1,000 ;IHC-Fr: 1:500 ;IF-Tissue: 1:500
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 200 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Neurofilament heavy polypeptide Recombinant Rabbit Monoclonal Antibody [JF99-07]?

The catalog number for Neurofilament heavy polypeptide Recombinant Rabbit Monoclonal Antibody [JF99-07] is ET1702-72.

What sizes are available for Neurofilament heavy polypeptide Recombinant Rabbit Monoclonal Antibody [JF99-07]?

Neurofilament heavy polypeptide Recombinant Rabbit Monoclonal Antibody [JF99-07] is available in the following size(s): 100 µL.

Is Neurofilament heavy polypeptide Recombinant Rabbit Monoclonal Antibody [JF99-07] in stock?

Neurofilament heavy polypeptide Recombinant Rabbit Monoclonal Antibody [JF99-07] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Neurofilament heavy polypeptide Recombinant Rabbit Monoclonal Antibody [JF99-07] used for?

Neurofilament-H (NF-H), for neurofilament heavy polypeptide, a member of the intermediate filament family, is a major component of neuronal cytoskeletons. Neurofilaments are dynamic structures; they contain phosphorylation sites for a large number of protein kinases, including protein kinase A, prot

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

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