Ctip2 Recombinant Rabbit Monoclonal Antibody [JF09-90]

About this product

Bcl-11a (CtIP-1, EVI9, B cell chronic lymphocytic leukemia (CLL)/lymphoma 11A) and Bcl-11b (CtIP-2, RIT1, B cell CLL/lymphoma 11B) genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.

Specifications

Catalog number

ET1702-76

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

ATL1 alpha antibody ATL1 antibody ATL1 beta antibody ATL1 gamma antibody ATL1-delta antibody B cell CLL/lymphoma 11B/T cell receptor delta constant region fusion protein antibody B cell lymphoma/leukemia 11B antibody B-cell CLL/lymphoma 11B (zinc finger protein) antibody B-cell CLL/lymphoma 11B antibody B-cell lymphoma/leukemia 11B antibody BC11B_HUMAN antibody BCL-11B antibody Bcl11b antibody BCL11B/TRDC fusion antibody COUP TF interacting protein 2 antibody COUP-TF interacting protein 2 antibody COUP-TF-interacting protein 2 antibody Ctip 2 antibody CTIP-2 antibody CTIP2 antibody hRIT1 alpha antibody hRit1 antibody Radiation induced tumor suppressor gene 1 antibody Radiation induced tumor suppressor gene 1 protein antibody Radiation-induced tumor suppressor gene 1 protein antibody Rit 1 antibody Rit1 antibody zinc finger protein hRit1 alpha antibody ZNF856B antibody

Abbreviation

BCL11B

Swiss Prot

Q9C0K0 Human, Q99PV8 Mouse,

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human Ctip2 aa 491-534 / 894.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC, IHC-Fr, IF-Tissue

Positive Control

LO2 cell lysate, THP-1 cell lysate, LO2, mouse brain tissue, human skin tissue, rat brain tissue, Jurkat.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:200-1:1,000 ;FC: 1:50-1:100 ;IHC-Fr: 1:500 ;IF-Tissue: 1:200-1:500

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 96 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes