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Product details

S100P Recombinant Rabbit Monoclonal Antibody [JF95-08]

Catalog number ET1702-82

Price for ET1702-82

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Size / count 100 µL

About this product

S-100 proteins are small dimeric members of the EF-Hand superfamily that participate in moderating intracellular calcium signals by binding to and regulating specific proteins in a calcium-dependent manner. S-100P is a survival factor that is associated with different types of tumors and can bind and regulate effector proteins. R1881, a synthetic androgen, regulates S-100P expression. S-100P interacts with a receptor for advanced glycation end products (RAGE) and activates it, thereby increasing the rates of cell growth, division, migration and invasion. This suggests that S-100P acts in an auto-crine manner through RAGE to trigger cell proliferation and survival. S-100P may also positively affect anchorage-independent growth to improve tumor formation. S-100P monomers strongly interact with one another, but not with other S-100 polypeptides, suggesting that homodimer formation is necessary for S-100P to function. The S-100P dimers are then stabilized by hydrophobic contacts.

Specifications

Catalog number
ET1702-82
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
MIG9 antibody Migration inducing gene 9 antibody Protein S100-E antibody Protein S100-P antibody Protein S100P antibody S100 calcium binding protein P antibody S100 calcium-binding protein P antibody S100 P antibody S100E antibody S100P antibody S100P_HUMAN antibody
Abbreviation
MIG9, S100P
Swiss Prot
P25815 Human
Cellular Locus
Nucleus, Cytoplasm, Cell projection.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human S100P aa 51-95 / 95.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P, IP
Positive Control
HepG2, Hela, human colon carcinoma tissue, human spleen tissue, human stomach tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IF-Cell: 1:50-1:200;IF-Tissue: 1:50-1:200;IHC-P: 1:50-1:200;IP: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 10 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for S100P Recombinant Rabbit Monoclonal Antibody [JF95-08]?

The catalog number for S100P Recombinant Rabbit Monoclonal Antibody [JF95-08] is ET1702-82.

What sizes are available for S100P Recombinant Rabbit Monoclonal Antibody [JF95-08]?

S100P Recombinant Rabbit Monoclonal Antibody [JF95-08] is available in the following size(s): 100 µL.

Is S100P Recombinant Rabbit Monoclonal Antibody [JF95-08] in stock?

S100P Recombinant Rabbit Monoclonal Antibody [JF95-08] is currently made to order / not held in immediate stock. Contact us for lead time.

What is S100P Recombinant Rabbit Monoclonal Antibody [JF95-08] used for?

S-100 proteins are small dimeric members of the EF-Hand superfamily that participate in moderating intracellular calcium signals by binding to and regulating specific proteins in a calcium-dependent manner. S-100P is a survival factor that is associated with different types of tumors and can bind an

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

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