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Product details

Thioredoxin Recombinant Rabbit Monoclonal Antibody [JF101-8]

Catalog number ET1702-90

Price for ET1702-90

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Size / count 100 µL

About this product

Thioredoxin (Trx) is a redox protein that is found in several species, such as bacteria, plants and mammals, and contains a conserved active site, consisting of Trp-Cys-Gly-Pro-Cys. Trx has several biological functions. It acts as a hydrogen donor for ribonucleotide reductase, which is critical for DNA synthesis, and modulates the DNA-binding activity of several transcription factors, including NFkB, AP-1, p53, TFIIIC and glucocorticoid receptor. Trx also stimulates cell growth, is an inhibitor of apoptosis and plays a role in the protection against oxidative stress. Drugs that inhibit Trx have antitumor activity, suggesting that Trx is involved in a variety of human diseases, including cancer. TrxR is a ubiquitously expressed flavoprotein that catalyzes the NADPH-dependent reduction of Trx as well as several other oxidized cellular components.

Specifications

Catalog number
ET1702-90
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
ADF antibody ATL derived factor antibody ATL-derived factor antibody DKFZp686B1993 antibody MGC61975 antibody SASP antibody Surface associated sulphydryl protein antibody Surface-associated sulphydryl protein antibody testicular tissue protein Li 199 antibody THIO_HUMAN antibody Thioredoxin antibody thioredoxin delta 3 antibody TRDX antibody TRX 1 antibody Trx antibody TRX1 antibody TXN antibody TXN delta 3 antibody TXN protein antibody zgc:92903 antibody
Abbreviation
TRX1, Trx, ADF, SASP, TXN
Swiss Prot
P10599 Human, P10639 Mouse, P11232 Rat
Cellular Locus
Nucleus, Cytoplasm, Secreted.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human Thioredoxin aa 78-105 / 105.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
HeLa cell lysate, 293T cell lysate, Mouse kidney tissue lysate, Mouse liver tissue lysate, Mouse colon tissue lysate, Rat colon tissue lysate, rat big intestine tissue, human small intestine tissue, mouse kidney tissue, human kidney tissue, Hela.
Concentration
1 mg/mL
Dilution
WB: 1:2,000-1:5,000 ;IHC-P: 1:400-1:1,000 ;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 12 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Thioredoxin Recombinant Rabbit Monoclonal Antibody [JF101-8]?

The catalog number for Thioredoxin Recombinant Rabbit Monoclonal Antibody [JF101-8] is ET1702-90.

What sizes are available for Thioredoxin Recombinant Rabbit Monoclonal Antibody [JF101-8]?

Thioredoxin Recombinant Rabbit Monoclonal Antibody [JF101-8] is available in the following size(s): 100 µL.

Is Thioredoxin Recombinant Rabbit Monoclonal Antibody [JF101-8] in stock?

Thioredoxin Recombinant Rabbit Monoclonal Antibody [JF101-8] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Thioredoxin Recombinant Rabbit Monoclonal Antibody [JF101-8] used for?

Thioredoxin (Trx) is a redox protein that is found in several species, such as bacteria, plants and mammals, and contains a conserved active site, consisting of Trp-Cys-Gly-Pro-Cys. Trx has several biological functions. It acts as a hydrogen donor for ribonucleotide reductase, which is critical for

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

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