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Product details

PGC1 alpha+beta Recombinant Rabbit Monoclonal Antibody [JF09-71]

Catalog number ET1702-96

Price for ET1702-96

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Size / count 100 µL

About this product

Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) is a protein that in humans is encoded by the PPARGC1A gene. PPARGC1A is also known as human accelerated region 20 (HAR20). It may, therefore, have played a key role in differentiating humans from apes. PGC-1α is the master regulator of mitochondrial biogenesis. PGC-1α is also the primary regulator of liver gluconeogenesis, inducing increased gene expression for gluconeogeneis. PGC-1α is a transcriptional coactivator that regulates the genes involved in energy metabolism. Peroxisome proliferator-activated receptor gamma coactivator 1-beta is a protein that in humans is encoded by the PPARGC1B gene. The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity.

Specifications

Catalog number
ET1702-96
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
LEM6 antibody Ligand effect modulator 6 antibody PERC antibody Peroxisome proliferative activated receptor, gamma, coactivator 1 alpha antibody Peroxisome proliferative activated receptor, gamma, coactivator 1 antibody Peroxisome proliferator activated receptor gamma coactivator 1 alpha antibody peroxisome proliferator-activated receptor gamma coactivator 1 beta antibody Peroxisome proliferator-activated receptor gamma coactivator 1-alpha antibody Peroxisome proliferator-activated receptor gamma coactivator 1-beta antibody peroxisome proliferator-activated receptor gamma, coactivator 1 beta antibody PGC 1 (alpha) antibody PGC 1 alpha antibody PGC 1v antibody PGC-1 (beta) antibody PGC-1-alpha antibody PGC-1-beta antibody PGC-1-related estrogen receptor alpha coactivator antibody PGC1 antibody PGC1 (alpha) antibody PGC1A antibody PGC1v antibody PPAR gamma coactivator 1 alpha antibody PPAR gamma coactivator 1 alpha 3 ligand effect modulator 6 antibody PPAR gamma coactivator 1 antibody PPAR gamma coactivator variant form antibody PPAR gamma coactivator-1beta antibody PPAR-gamma coactivator 1-alpha antibody PPAR-gamma coactivator 1-beta antibody PPARGC 1 alpha antibody PPARGC-1-alpha antibody PPARGC-1-beta antibody PPARGC1 antibody PPARGC1A antibody Ppargc1b antibody PRGC1_HUMAN antibody PRGC2_HUMAN antibody
Abbreviation
PGC-1-alpha, PPAR-gamma coactivator 1-alpha, PPARGC-1-alpha, PPARGC1A, PGC-1-beta, PPAR-gamma coactivator 1-beta, PPARGC-1-beta, PPARGC1B
Swiss Prot
Q86YN6 Human, Q9UBK2 Human, 415302 Mouse, O70343 Mouse, Q8VHJ7 Mouse, Q811R2 Rat, Q9QYK2 Rat
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human PGC1 alpha aa 755-798 /798 and aa 269-323 /798.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
Mouse brain tissue lysate, rat brain tissue lysate, SK-Br-3 cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 91/113 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for PGC1 alpha+beta Recombinant Rabbit Monoclonal Antibody [JF09-71]?

The catalog number for PGC1 alpha+beta Recombinant Rabbit Monoclonal Antibody [JF09-71] is ET1702-96.

What sizes are available for PGC1 alpha+beta Recombinant Rabbit Monoclonal Antibody [JF09-71]?

PGC1 alpha+beta Recombinant Rabbit Monoclonal Antibody [JF09-71] is available in the following size(s): 100 µL.

Is PGC1 alpha+beta Recombinant Rabbit Monoclonal Antibody [JF09-71] in stock?

PGC1 alpha+beta Recombinant Rabbit Monoclonal Antibody [JF09-71] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PGC1 alpha+beta Recombinant Rabbit Monoclonal Antibody [JF09-71] used for?

Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) is a protein that in humans is encoded by the PPARGC1A gene. PPARGC1A is also known as human accelerated region 20 (HAR20). It may, therefore, have played a key role in differentiating humans from apes. PGC-1α is the maste

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

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