SERCA2 Recombinant Rabbit Monoclonal Antibody [JM10-20]

About this product

ATP2A2 also known as sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) is an ATPase associated with Darier's disease and Acrokeratosis verruciformis. This gene encodes one of the SERCA Ca (2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

Catalog number

ET1703-01

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

AT2A2_HUMAN antibody Atp2a2 antibody ATP2B antibody ATPase Ca++ transporting cardiac muscle slow twitch 2 antibody Calcium pump 2 antibody Calcium-transporting ATPase sarcoplasmic reticulum type antibody Calcium-transporting ATPase sarcoplasmic reticulum type slow twitch skeletal muscle isoform antibody Cardiac Ca2+ ATPase antibody DAR antibody DD antibody Endoplasmic reticulum class 1/2 Ca (2+) ATPase antibody MGC45367 antibody Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 antibody SERCA 2 antibody SERCA2 antibody serca2a antibody slow twitch skeletal muscle isoform antibody SR Ca (2+)-ATPase 2 antibody

Abbreviation

SERCA2, SR Ca (2+)-ATPase 2, ATP2A2

Swiss Prot

P16615 Human, O55143 Mouse, P11507 Rat

Cellular Locus

Endoplasmic reticulum membrane, Sarcoplasmic reticulum membrane.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human SERCA2 aa 999-1,042 / 1,042.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, FC

Positive Control

A549 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, A549, NIH/3T3, PC-12, human tonsil tissue, human kidney tissue, mouse skeletal muscle tissue, mouse skin tissue, human liver carcinoma tissue, mouse kidney tissue, mouse heart tissue, rat kidney tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IF-Cell: 1:100 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:500 ;FC: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 115 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes