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Product details

Thioredoxin Recombinant Rabbit Monoclonal Antibody [JM10-019]

Catalog number ET1703-03

Price for ET1703-03

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Size / count 100 µL

About this product

Thioredoxin (Trx) is a redox protein that is found in several species, such as bacteria, plants and mammals, and contains a conserved active site, consisting of Trp-Cys-Gly-Pro-Cys. Trx has several biological functions. It acts as a hydrogen donor for ribonucleotide reductase, which is critical for DNA synthesis, and modulates the DNA-binding activity of several transcription factors, including NFkB, AP-1, p53, TFIIIC and glucocorticoid receptor. Trx also stimulates cell growth, is an inhibitor of apoptosis and plays a role in the protection against oxidative stress. Drugs that inhibit Trx have antitumor activity, suggesting that Trx is involved in a variety of human diseases, including cancer. TrxR is a ubiquitously expressed flavoprotein that catalyzes the NADPH-dependent reduction of Trx as well as several other oxidized cellular components.

Specifications

Catalog number
ET1703-03
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
ADF antibody ATL derived factor antibody ATL-derived factor antibody DKFZp686B1993 antibody MGC61975 antibody SASP antibody Surface associated sulphydryl protein antibody Surface-associated sulphydryl protein antibody testicular tissue protein Li 199 antibody THIO_HUMAN antibody Thioredoxin antibody thioredoxin delta 3 antibody TRDX antibody TRX 1 antibody Trx antibody TRX1 antibody TXN antibody TXN delta 3 antibody TXN protein antibody zgc:92903 antibody
Abbreviation
Trx, ADF, SASP, TXN
Swiss Prot
P10599 Human
Cellular Locus
Nucleus, Cytoplasm, Secreted.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human Thioredoxin aa 6-50 / 105.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P
Positive Control
Hela cell lysates, Hela, MCF-7, SKOV-3, human fallopian tube tissue, human uterus tissue, human small intestine tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IF-Cell: 1:100-1:200 ;IF-Tissue: 1:100-1:200 ;IHC-P: 1:400
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 12 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Thioredoxin Recombinant Rabbit Monoclonal Antibody [JM10-019]?

The catalog number for Thioredoxin Recombinant Rabbit Monoclonal Antibody [JM10-019] is ET1703-03.

What sizes are available for Thioredoxin Recombinant Rabbit Monoclonal Antibody [JM10-019]?

Thioredoxin Recombinant Rabbit Monoclonal Antibody [JM10-019] is available in the following size(s): 100 µL.

Is Thioredoxin Recombinant Rabbit Monoclonal Antibody [JM10-019] in stock?

Thioredoxin Recombinant Rabbit Monoclonal Antibody [JM10-019] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Thioredoxin Recombinant Rabbit Monoclonal Antibody [JM10-019] used for?

Thioredoxin (Trx) is a redox protein that is found in several species, such as bacteria, plants and mammals, and contains a conserved active site, consisting of Trp-Cys-Gly-Pro-Cys. Trx has several biological functions. It acts as a hydrogen donor for ribonucleotide reductase, which is critical for

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

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