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Product details

Parvalbumin Recombinant Rabbit Monoclonal Antibody [JM100-08]

Catalog number ET1703-15

Price for ET1703-15

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Size / count 100 µL

About this product

Parvalbumin (PV) is a calcium-binding protein with low molecular weight (typically 9-11 kDa). In humans, it is encoded by the PVALB gene. It is not a member of the albumin family; it is named for its size (parv-, from Latin parvus small) and its ability to coagulate. It has three EF hand motifs and is structurally related to calmodulin and troponin C. Parvalbumin is found in fast-contracting muscles, where its levels are highest, as well as in the brain and some endocrine tissues. Parvalbumin is a small, stable protein containing EF-hand type calcium binding sites. It is involved in calcium signaling. Calcium binding proteins like parvalbumin play a role in many physiological processes, namely cell-cycle regulation, second messenger production, muscle contraction, organization of microtubules and phototransduction. Therefore, calcium-binding proteins must distinguish calcium in the presence of high concentrations of other metal ions. The mechanism for the calcium selectivity has been extensively studied.

Specifications

Catalog number
ET1703-15
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
D22S749 antibody MGC116759 antibody Parvalbumin alpha antibody PRVA_HUMAN antibody PVALB antibody
Abbreviation
PVALB
Swiss Prot
P20472 Human, P32848 Mouse, P02625 Rat
Cellular Locus
Axon, cytoplasm, synapse.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human Paravalbumin aa 1-110 / 110.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IHC-Fr, IF-Tissue, IP
Positive Control
RPMI 8226 cell lysate, human kidney tissue, mouse kidney tissue, mouse cerebellum tissue, rat cerebellum tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:200-1:1,000 ;IHC-Fr: 1:500 ;IF-Tissue: 1:200 ;IP: 1-2μg/sample
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 12 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Parvalbumin Recombinant Rabbit Monoclonal Antibody [JM100-08]?

The catalog number for Parvalbumin Recombinant Rabbit Monoclonal Antibody [JM100-08] is ET1703-15.

What sizes are available for Parvalbumin Recombinant Rabbit Monoclonal Antibody [JM100-08]?

Parvalbumin Recombinant Rabbit Monoclonal Antibody [JM100-08] is available in the following size(s): 100 µL.

Is Parvalbumin Recombinant Rabbit Monoclonal Antibody [JM100-08] in stock?

Parvalbumin Recombinant Rabbit Monoclonal Antibody [JM100-08] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Parvalbumin Recombinant Rabbit Monoclonal Antibody [JM100-08] used for?

Parvalbumin (PV) is a calcium-binding protein with low molecular weight (typically 9-11 kDa). In humans, it is encoded by the PVALB gene. It is not a member of the albumin family; it is named for its size (parv-, from Latin parvus small) and its ability to coagulate. It has three EF hand motifs and

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

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