FGF2 Recombinant Rabbit Monoclonal Antibody [JM28-10]

About this product

FGF2, also known as basic fibroblast growth factor (bFGF) and FGF-β, is a growth factor and signaling protein encoded by the FGF2 gene. It binds to and exerts effects via specific fibroblast growth factor receptor (FGFR) proteins, themselves a family of closely related molecules. Fibroblast growth factor protein was first purified in 1975; soon thereafter three variants were isolated: 'basic FGF' (FGF2); Heparin-binding growth factor-2; and Endothelial cell growth factor-2. Gene sequencing revealed that this group is the same FGF2 protein and is a member of a family of FGF proteins. Like other FGF family members, basic fibroblast growth factor possess broad mitogenic and cell survival activities, and is involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. In normal tissue, bFGF is present in basement membranes and in the subendothelial extracellular matrix of blood vessels. It stays membrane-bound as long as there is no signal peptide.

Specifications

Catalog number

ET1703-18

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Basic fibroblast growth factor antibody Basic fibroblast growth factor bFGF antibody BFGF antibody FGF 2 antibody FGF B antibody FGF-2 antibody Fgf2 antibody FGF2 basic antibody FGF2_HUMAN antibody FGFB antibody Fibroblast growth factor 2 (basic) antibody Fibroblast growth factor 2 antibody Fibroblast growth factor, basic antibody HBGF 2 antibody HBGF-2 antibody HBGF2 antibody HBGH 2 antibody HBGH2 antibody Heparin binding growth factor 2 precursor antibody Heparin-binding growth factor 2 antibody Prostatropin antibody

Abbreviation

bFGF, HBGF-2

Swiss Prot

P09038 Human, P15655 Mouse

Cellular Locus

Secreted, Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Synthetic peptide within Human FGF2 aa 121-170 / 288.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IP, FC, IHC-P

Positive Control

K-562 cell lysate, U-87 MG cell lysate, HeLa cell lysate, 293T cell lysate, human breast tissue, human prostate tissue, mouse trachea tissue, Jurkat.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:1,000 ;IP: 1-2μg/sample ;FC: 1:50-1:100 ;IHC-P: 1:200-1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 31 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes