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![ERCC1 Recombinant Rabbit Monoclonal Antibody [JM10-07] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8c061270361ea81ca0/imageurl/et1703-19.webp)
Product details
Catalog number ET1703-19
Price for ET1703-19
Size / count 100 µL
DNA excision repair protein ERCC-1 is a protein that in humans is encoded by the ERCC1 gene. Together with ERCC4, ERCC1 forms the ERCC1-XPF enzyme complex that participates in DNA repair and DNA recombination. Cells with disabling mutations in ERCC1 are more sensitive than normal to particular DNA damaging agents, including ultraviolet (UV) radiation and to chemicals that cause crosslinking between DNA strands. Genetically engineered mice with disabling mutations in ERCC1 have defects in DNA repair, accompanied by metabolic stress-induced changes in physiology that result in premature aging. Complete deletion of ERCC1 is incompatible with viability of mice, and no human individuals have been found with complete (homozygous) deletion of ERCC1. Rare individuals in the human population harbor inherited mutations that impair the function of ERCC1. When the normal genes are absent, these mutations can lead to human syndromes, including Cockayne syndrome (CS) and COFS.
The catalog number for ERCC1 Recombinant Rabbit Monoclonal Antibody [JM10-07] is ET1703-19.
ERCC1 Recombinant Rabbit Monoclonal Antibody [JM10-07] is available in the following size(s): 100 µL.
ERCC1 Recombinant Rabbit Monoclonal Antibody [JM10-07] is currently made to order / not held in immediate stock. Contact us for lead time.
DNA excision repair protein ERCC-1 is a protein that in humans is encoded by the ERCC1 gene. Together with ERCC4, ERCC1 forms the ERCC1-XPF enzyme complex that participates in DNA repair and DNA recombination. Cells with disabling mutations in ERCC1 are more sensitive than normal to particular DNA d
No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.
Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.
The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.
