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Product details

SMC3 Recombinant Rabbit Monoclonal Antibody [JM10-75]

Catalog number ET1703-35

Price for ET1703-35

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Size / count 100 µL

About this product

The SMC (structural maintenance of chromosomes) family of proteins form heterodimeric complexes that modulate sister chromatid cohesion and chromosome condensation for mitosis. The two distinct classes of SMC protein complexes are comprised of SMC1 (also designated SB1.8) with SMC3 (also designated HCAP for human chromosome-associated protein and Bamacan for the secreted proteoglycan), and SMC2 (also designated hCAP-E) with SMC4 (also designated hCAP-C). The SMC1/SMC3 complex is required for metaphase progression in mitotic cells and functions independently of the SMC2/SMC4 complex during the cell cycle. SMC1 is ubiqitiously expressed in various human tissues, including thymus, testis, and colon. SMC3 is expressed as a nuclear protein in the colon, but can also occur as a secreted proteoglycan expressed in testis and brain. The secreted proteoglycan contains several glycosylation sites and is thought to play a role in basement membrane physiology.

Specifications

Catalog number
ET1703-35
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
BAM antibody Bamacan antibody Basement membrane associated chondroitin proteoglycan antibody Basement membrane-associated chondroitin proteoglycan antibody BMH antibody CDLS3 antibody chondroitin sulfate proteoglycan 6 (bamacan) antibody Chondroitin sulfate proteoglycan 6 antibody Chromosome associated polypeptide antibody Chromosome-associated polypeptide antibody CSPG 6 antibody CSPG6 antibody hCAP antibody Human chromosome associated polypeptide antibody im:7142991 antibody SMC 3 antibody SMC protein 3 antibody SMC-3 antibody smc3 antibody SMC3_HUMAN antibody SMC3L1 antibody Structural maintenance of chromosome 3 antibody Structural maintenance of chromosomes 3 antibody Structural maintenance of chromosomes protein 3 antibody u:fb22e01 antibody wu:fc30d07 antibody
Abbreviation
SMC protein 3, SMC-3, Bamacan, hCAP
Swiss Prot
Q9UQE7 Human, Q9CW03 Mouse, P97690 Rat
Cellular Locus
Centromere, Chromosome, Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Zebrafish
Immunogen
Synthetic peptide within Human SMC3 aa 1994-1217 / 1217.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P, FC
Positive Control
HepG2 cell lysate, NIH-3T3 cell lysate, PC12 cell lysate, Hela, HepG2, NIH-3T3, human tonsil tissue, human colon cancer tissue, human kidney tissue, mouse colon tissue, zebrafish tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:5,000;IF-Cell: 1:100-1:500;IF-Tissue: 1:100-1:500;IHC-P: 1:50-1:200;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 142 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for SMC3 Recombinant Rabbit Monoclonal Antibody [JM10-75]?

The catalog number for SMC3 Recombinant Rabbit Monoclonal Antibody [JM10-75] is ET1703-35.

What sizes are available for SMC3 Recombinant Rabbit Monoclonal Antibody [JM10-75]?

SMC3 Recombinant Rabbit Monoclonal Antibody [JM10-75] is available in the following size(s): 100 µL.

Is SMC3 Recombinant Rabbit Monoclonal Antibody [JM10-75] in stock?

SMC3 Recombinant Rabbit Monoclonal Antibody [JM10-75] is currently made to order / not held in immediate stock. Contact us for lead time.

What is SMC3 Recombinant Rabbit Monoclonal Antibody [JM10-75] used for?

The SMC (structural maintenance of chromosomes) family of proteins form heterodimeric complexes that modulate sister chromatid cohesion and chromosome condensation for mitosis. The two distinct classes of SMC protein complexes are comprised of SMC1 (also designated SB1.8) with SMC3 (also designated

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

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