CD32 Recombinant Rabbit Monoclonal Antibody [JM10-70]

About this product

CD32 (also designated Fc gamma RII) is a low affinity receptor for the Fc fragment of aggregated IgG. CD32 is responsible for the clearance of immunocomplexes by macrophages and also plays an important role in the regulation of antibody production by B cells. IgG can noncooperatively bind either one or two highly glycosylated CD32 molecules, and this binding delivers a negative signal for B cells . CD32 exists as several isoforms that are produced by alternative splicing of three distinct genes, A, B, and C . These isoforms are designated FcgRIIA, FcgRIIB1, FcgRIIB3, and FcgRIIC . All isoforms are present on monocytes, placental trophoblasts and endothelial cells . In addition, the FcgRIIB forms are present on B lymphocytes, and the FcgRIIA and FcgRIIC forms are found on neutrophils.

Specifications

Catalog number

ET1703-43

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

CD32 antibody CD32A antibody CD32B antibody CD32C antibody CDw32 antibody Fc fragment of IgG low affinity IIa receptor antibody Fc fragment of IgG low affinity IIa receptor for (CD32) antibody Fc fragment of IgG low affinity IIb receptor antibody Fc fragment of IgG low affinity IIb receptor for (CD32) antibody Fc fragment of IgG low affinity IIc receptor antibody Fc fragment of IgG low affinity IIc receptor for (CD32) antibody Fc fragment of IgG, low affinity II, receptor for (CD32) antibody Fc fragment of IgG, low affinity IIa, receptor (CD32) antibody Fc fragment of IgG, low affinity IIb, receptor (CD32) antibody Fc gamma receptor IIB antibody Fc gamma receptor IIC antibody Fc gamma RII a antibody Fc gamma RII b antibody Fc gamma RII c antibody Fc gamma RIIb antibody Fc gamma RIIc antibody Fc receptor, IgG, low affinity IIb antibody Fc-gamma RII-a antibody Fc-gamma RII-b antibody Fc-gamma RII-c antibody Fc-gamma-RIIa antibody FC-gamma-RIIB antibody Fc-GAMMA-RIIC antibody Fc[g]RII antibody FCG2 antibody FCG2A_HUMAN antibody FcGR antibody FCGR2 antibody FCGR2A antibody FCGR2A1 antibody FCGR2B antibody FCGR2C antibody Fcgr3 antibody Fcgr3a antibody FcgRII antibody Fcr-2 antibody Fcr-3 antibody FcRII a antibody FCRII antibody FcRII b antibody FcRII c antibody FcRII-a antibody FcRIIC antibody IGFR2 antibody IgG Fc receptor II a antibody IgG Fc receptor II b antibody IgG Fc receptor II beta antibody IgG Fc receptor II c antibody IgG Fc receptor II-a antibody IgG Fc receptor II-b antibody IgG Fc receptor II-c antibody Immunoglobulin G Fc receptor II antibody Immunoglobulin G Fc receptor II c antibody Low affinity immunoglobulin gamma Fc region receptor II antibody Low affinity immunoglobulin gamma Fc region receptor II-a antibody Low affinity immunoglobulin gamma Fc region receptor II-b antibody Low affinity immunoglobulin gamma Fc region receptor II-c antibody Ly-17 antibody Ly-m20 antibody LyM-1 antibody Lymphocyte antigen 17 antibody

Abbreviation

IgG Fc receptor II-a, Fc-gamma-RIIa, FcRII-a, FCGR2A

Swiss Prot

P12318 Human

Cellular Locus

Cell membrane.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant protein within Human CD32 aa 23-274 / 310.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IF-Cell

Positive Control

Human lung tissue lysates, human tonsil tissue, human spleen tissue, human pancreas tissue, K-562.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:5,000 ;IHC-P: 1:50-1:400 ;IF-Cell: 1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 35 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes