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Product details

CaMKII alpha Recombinant Rabbit Monoclonal Antibody [JM11-07]

Catalog number ET1703-54

Price for ET1703-54

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Size / count 100 µL

About this product

The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is a ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes designated α, β, γ and δ, which may or may not be co-expressed in the same tissue type. CaMKIV is stimulated by Ca2+ and CaM but also requires phosphorylation by a CaMK for full activation. Stimulation of the T cell receptor CD3 signaling complex with an anti-CD3 monoclonal antibody leads to a 10-40 fold increase in CaMKIV activity. An additional kinase, CaMKK, functions to activate CaMKI through the specific phosphorylation of the regulatory Threonine residue at position 177.

Specifications

Catalog number
ET1703-54
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Alpha CaMKII antibody Calcium calmodulin dependent protein kinase II antibody Calcium/calmodulin dependent protein kinase II alpha B subunit antibody Calcium/calmodulin dependent protein kinase type II alpha chain antibody Calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha antibody Calcium/calmodulin-dependent protein kinase II alpha antibody Calcium/calmodulin-dependent protein kinase II-alpha antibody Calcium/calmodulin-dependent protein kinase type II subunit alpha antibody Calcium/calmodulin-dependent protein kinase type IIA antibody CaM kinase II alpha chain antibody CaM kinase II alpha subunit antibody CaM kinase II subunit alpha antibody CaMK II alpha subunit antibody CaMK-II subunit alpha antibody Camk2a antibody CAMKA antibody CaMKII antibody CaMKIINalpha antibody EC 2.7.11.17 antibody KCC2A_HUMAN antibody KIAA0968 antibody MGC123320 antibody MGC139375 antibody MGC155201 antibody mKIAA0968 antibody PK2CDD antibody PKCCD antibody R74975 antibody zgc:112538 antibody zgc:123320 antibody
Abbreviation
CaM kinase II subunit alpha, CaMK-II subunit alpha
Swiss Prot
Q9UQM7 Human, P11798 Mouse, P11275 Rat
Cellular Locus
Cell junction, Cell projection, Synapse.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human CaMKII alpha aa 37-71 / 478.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IP, FC, IHC-P, IF-Tissue, IF-Cell, IHC-Fr
Positive Control
Mouse brain tissue, rat brain tissue lysates, rat testis tissue, mouse cerebellum tissue, rat brain tissue, Neuro-2a.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100 ;IP: 1:10-1:50 ;IF-Tissue: 1:50 ;IF-Cell: 1:100 ;IHC-Fr: 1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 54 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for CaMKII alpha Recombinant Rabbit Monoclonal Antibody [JM11-07]?

The catalog number for CaMKII alpha Recombinant Rabbit Monoclonal Antibody [JM11-07] is ET1703-54.

What sizes are available for CaMKII alpha Recombinant Rabbit Monoclonal Antibody [JM11-07]?

CaMKII alpha Recombinant Rabbit Monoclonal Antibody [JM11-07] is available in the following size(s): 100 µL.

Is CaMKII alpha Recombinant Rabbit Monoclonal Antibody [JM11-07] in stock?

CaMKII alpha Recombinant Rabbit Monoclonal Antibody [JM11-07] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CaMKII alpha Recombinant Rabbit Monoclonal Antibody [JM11-07] used for?

The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is a ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+and calmodulin (CaM) and has been impl

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

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