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Product details

FKBP12 Recombinant Rabbit Monoclonal Antibody [JM11-09]

Catalog number ET1703-55

Price for ET1703-55

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Size / count 100 µL

About this product

Immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases which bind to and mediate the effects of immunosuppressive drugs such as Cyclosporin, FK506 and Rapamycin. FKBP12.6, also known as FK506-binding protein 1B, is a 108 amino acid immunophilin belonging to the FKBP-type PPIase family. Subcellularly localized to the cytoplasm, FKBP12.6 binds to RyR in cardiac muscle sarcoplasmic reticulum and possibly plays a unique physiological role in excitation-contraction coupling in cardiac muscle. FKBP12.6 also catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Ubiquitously expressed, FKBP12.6 is found at highest levels in brain and thymus. FKBP12.6 is expressed as two isoforms produced by alternative splicing.

Specifications

Catalog number
ET1703-55
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
12 kDa FK506-binding protein antibody 12 kDa FKBP antibody Calstabin 1 antibody FK506 binding protein 1 antibody FK506 binding protein 12 antibody FK506 binding protein 1A (12kD) antibody FK506 binding protein 1A 12kDa antibody FK506 binding protein 1A antibody FK506 binding protein T cell 12 kD antibody FK506 binding protein, T cell, 12 kD antibody FK506 binding protein12 antibody FK506-binding protein 1A antibody FKB1A_HUMAN antibody FKBP 12 antibody FKBP 1A antibody FKBP-12 antibody FKBP-1A antibody FKBP1 antibody FKBP12 antibody FKBP12 Exip3 antibody FKBP12C antibody fkbp1a antibody Immunophilin FKBP12 antibody Peptidyl prolyl cis trans isomerase antibody Peptidyl-prolyl cis-trans isomerase FKBP1A antibody PKC12 antibody PKCI2 antibody PPIase antibody PPIase FKBP1A antibody Protein kinase C inhibitor 2 antibody Rotamase antibody
Abbreviation
PPIase FKBP1A, 12 kDa FKBP, FKBP-12, FKBP-1A, FKBP1A
Swiss Prot
P62942 Human, P26883 Mouse, Q62658 Rat
Cellular Locus
Cytoplasm, Membrane, Sarcoplasmic reticulum.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human FKBP12 aa 76-108 / 108.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
SH-SY5Y cell lysate, PC-12 cell lysate, Mouse brain tissue lysate, Rat brain tissue lysate.
Concentration
1 mg/mL
Dilution
WB: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 12 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for FKBP12 Recombinant Rabbit Monoclonal Antibody [JM11-09]?

The catalog number for FKBP12 Recombinant Rabbit Monoclonal Antibody [JM11-09] is ET1703-55.

What sizes are available for FKBP12 Recombinant Rabbit Monoclonal Antibody [JM11-09]?

FKBP12 Recombinant Rabbit Monoclonal Antibody [JM11-09] is available in the following size(s): 100 µL.

Is FKBP12 Recombinant Rabbit Monoclonal Antibody [JM11-09] in stock?

FKBP12 Recombinant Rabbit Monoclonal Antibody [JM11-09] is currently made to order / not held in immediate stock. Contact us for lead time.

What is FKBP12 Recombinant Rabbit Monoclonal Antibody [JM11-09] used for?

Immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases which bind to and mediate the effects of immunosuppressive drugs such as Cyclosporin, FK506 and Rapamycin. FKBP12.6, also known as FK506-binding protein 1B, is a 108 amino acid immunophilin belonging to the FKBP-type

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

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